Results 251 to 260 of about 6,711,226 (342)

Globalization and Forces for Change in Higher Education

, 2015
Philip G. Altbach
openalex   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Genomic Evidence for Local Adaptation to Elevation and Climate Sheds New Light on Variable Responses to Global Change in American Pikas (Ochotona princeps). [PDF]

Mol Ecol
Beever EA, Osterhoudt E, Linck EB.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Plant traits and associated ecological data from global change experiments and climate gradients in Norway. [PDF]

Sci Data
Vandvik V, Halbritter AH, Macias-Fauria M, Maitner BS, Michaletz ST, Telford RJ, Bison N, Chacon-Labella J, Cotner S, Egelkraut D, Garen J, Gaudard J, Geange SR, Rosati MA, Andersen EAS, Ahler SJ, Atkinson J, Baumane M, Bradler PM, Dawson HR, Eckberg J, Elsy AD, Erkelenz J, Eshelman SE, Guclu C, Gullvåg R, Gya R, Hartford S, Hayden MT, Holle MJM, Kullberg AT, Lepley K, Correia M, Löwenstein CE, Maré C, Mauki D, Navarro J, Oberholzer B, Olivier B, Olson AN, Ray CA, von Oppen J, Vorstenbosch T, Wang JA, Enquist BJ.   +44 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Soil microbial responses to multiple global change factors as assessed by metagenomics. [PDF]

Nat Commun
Rodríguez Del Río Á, Scheu S, Rillig MC.   +2 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors. [PDF]

Proc Natl Acad Sci U S A
Brennan RS, deMayo JA, Finiguerra M, Baumann H, Dam HG, Pespeni MH.   +5 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source