Results 61 to 70 of about 6,711,226 (342)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Global Climate Change Impacts on Crop Production in Hungary [PDF]

, 2007
Global climate change is one of the major issues today. There is a continuous rise in temperature escorted by the increasing frequencies of weather anomalies.
Birkás, Márta, Jolánkai, Márton
core  

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Low-cost simulation models for soft-tissue procedures for medical student education in Rwanda

BMC Medical Education
Background Simulation-based training (SBT) enhances medical education but is often limited in low-resource settings. This study aimed to describe the development, use, and cost implication of three low-cost models of soft tissue lesions for SBT of ...
Rachel E. Wittenberg, Mayte Bryce-Alberti, Natnael Z. Shimelash, Ornella Masimbi, Lauren E. Kratky, Avery A. Thompson, Omar Alali, Madeleine Carroll, Sarah R. Nuss, Matthew T. Hey, Lilli Gordon, Radzi Hamzah, Kiana Winslow, Isaac G. Alty, Rashi Jhunjhunwala, Callum Forbes, Andrew Eyre, Robert Riviello, Abebe Bekele, Geoffrey A. Anderson, Barnabas Tobi Alayande   +20 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Millennium time-scale experiments on climate-carbon cycle with doubled CO2 concentration

Progress in Earth and Planetary Science, 2020
Earth system models (ESMs) are commonly used for simulating the climate–carbon (C) cycle and for projecting future global warming. While ESMs are most often applied to century-long climate simulations, millennium-long simulations, which have been ...
Tomohiro Hajima, Akitomo Yamamoto, Michio Kawamiya, Xuanming Su, Michio Watanabe, Rumi Ohgaito, Hiroaki Tatebe   +6 more
doaj   +1 more source

Patterns of change: whose fingerprint is seen in global warming? [PDF]

, 2011
Attributing observed climate change to causes is challenging. This letter communicates the physical arguments used in attribution, and the statistical methods applied to explore to what extent different possible causes can be used to explain the recent ...
, Claudia Tebaldi, Francis Zwiers, Gabriele Hegerl, Hasselmann K, Hegerl G C, IPCC, Jansen E, Kennedy J J, Mahlstein I, Randall D A, von Storch H   +11 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Global climate change : greenhouse effect [PDF]

, 1992
One of the main problems caused by climate change is the greenhouse effect. Human activities emit so-called greenhouse gases into the atmosphere, such as carbon dioxide which is produced through fossil fuel burning.
Attard, David
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source