Results 71 to 80 of about 6,391,118 (308)

Managerial Economics and Global Competition

open access: yesSymphonya, 2005
Global managerial economics tends to emerge in conditions of strong, continuous competitive tension, in contexts that are open and subject to political, social and technological instability.
Silvio M. Brondoni
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Ouverture de 'Intangible Assets & Global Competition' [PDF]

open access: yes
Since the early 80s, the global economy has radically changed companies, manufacturing system and products. Global managerial economics demands ramified, far-flung and strongly interconnected organisations (networks).
Silvio Mario Brondoni
core  

GCode For Siemens Competition

open access: yes, 2017
<p>For Siemens Science Competition</p> ...
Competition Entrant   +1 more
core   +1 more source

INDUSTRIAL INTEGRATION OF rUSSIA AND UKRAINE UNDER GLOBAL COMPETITION

open access: yesRussian Journal of Economics and Law, 2013
Objective: basing on the facts of economic reality of Russia and Ukraine and the existing industrial interconnections between them, to reveal the priority directions of interaction under the increasing global competition.
N. Y. Sopilko, N. A. Navrotskaya
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Competition and the State

open access: yes, 2014
Competition and the State analyzes the role of the state across a number of dimensions as it relates to competition law and policy across a number of dimensions.

core  

GLOBAL COMPETITION AND ROMANIA’S NATIONAL COMPETITIVE ADVANTAGE [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
Analyzing products and services around us it is clear that most of them are the result of production factors, labor and capital becoming more international and increasingly less and less national. We are witnessing the globalization of markets and production, to a large global integration and interdependence, increase personalization of production and ...
Pop Nicolae Alexandru   +2 more
openaire   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

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