Results 41 to 50 of about 1,624,337 (307)

Complex spatial organization in a simple model of resource allocation

open access: yes, 2000
A dynamical model for the distribution of resources between competing agents is studied. While global competition leads to the accumulation of all the resources by a single agent, local competition allows for a wider resource distribution. Multiplicative
Zanette, Damian H.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Planned Obsolescence, Total Quality, Zero Defects and Global Competition

open access: yesSymphonya, 2018
A global firm's success is conditioned by its ability to manage the system of intangible corporate assets (corporate culture, corporate identity, and information system) and intangible product assets (product design, brand equity and pre/after-sales ...
Silvio M. Brondoni
doaj   +1 more source

2008 Annual Report [PDF]

open access: yes, 2008
[Excerpt] It has been a challenging year for labor relations in the United States. Workers experienced heightened concern for their personal financial situations and job security.
Federal Mediation & Conciliation Service
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Ouverture de ‘The 4th Industrial Revolution. Business Model Innovation & Global Competition’

open access: yesSymphonya, 2018
The 4th Industrial Revolution is expected to lead to a paradigm shift in business, with strong effects on manufacturing and service processes, and consequent competitive advantages for firms, industries, and regional/national systems.
Silvio M. Brondoni, Enrico Zaninotto
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

GLOBAL COMPETITION AND ROMANIA’S NATIONAL COMPETITIVE ADVANTAGE [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
Analyzing products and services around us it is clear that most of them are the result of production factors, labor and capital becoming more international and increasingly less and less national. We are witnessing the globalization of markets and production, to a large global integration and interdependence, increase personalization of production and ...
Pop Nicolae Alexandru   +2 more
openaire   +1 more source

Regulation mechanisms in spatial stochastic development models

open access: yes, 2008
The aim of this paper is to analyze different regulation mechanisms in spatial continuous stochastic development models. We describe the density behavior for models with global mortality and local establishment rates.
A. Lenard   +19 more
core   +2 more sources

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