Results 91 to 100 of about 6,234,642 (356)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Global exponential convergence to variational traveling waves in cylinders

, 2011
We prove, under generic assumptions, that the special variational traveling wave that minimizes the exponentially weighted Ginzburg-Landau functional associated with scalar reaction-diffusion equations in infinite cylinders is the long-time attractor for
Barenblatt G. I., Berestycki H., C. B. Muratov, Gallay T., Gallay T., Kanel' Y. I., Kanel' Y. I., Kolmogorov A. N., Lions P.-L., M. Novaga, Uchiyama K.   +10 more
core   +1 more source

A globally convergent algorithm for MPCC

EURO Journal on Computational Optimization, 2015
We propose a penalty formulation based on the new regularization scheme for mathematical programs with complementarity constraints (MPCCs). We present an active set method which solves a sequence of penalty-regularized problems. We study global convergence properties of the method under the MPCC-linear independence constraint qualification.
Abdelhamid Benchakroun, Abdeslam Kadrani, Jean-Pierre Dussault   +2 more
openaire   +3 more sources

Global energy use: Decoupling or convergence? [PDF]

Energy Economics, 2014
We examine the key factors driving change in energy use globally over the past four decades. We test for both strong decoupling where economic growth has less effect on energy use as income increases, and weak decoupling where energy use declines overtime in richer countries, ceteris paribus.
Csereklyei, Zsuzsanna, Stern, David
openaire   +4 more sources

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

A globally convergent incremental Newton method [PDF]

Mathematical Programming, 2015
Motivated by machine learning problems over large data sets and distributed optimization over networks, we develop and analyze a new method called incremental Newton method for minimizing the sum of a large number of strongly convex functions. We show that our method is globally convergent for a variable stepsize rule.
Gurbuzbalaban, Mert, Ozdaglar, Asuman E., Parrilo, Pablo A.   +2 more
openaire   +6 more sources

UR‐cycleGAN: Denoising full‐body low‐dose PET images using cycle‐consistent Generative Adversarial Networks

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to develop a CycleGAN based denoising model to enhance the quality of low‐dose PET (LDPET) images, making them as close as possible to standard‐dose PET (SDPET) images. Methods Using a Philips Vereos PET/CT system, whole‐body PET images of fluorine‐18 fluorodeoxyglucose (18F‐FDG) were acquired from 37 patients to ...
Yang Liu, ZhiWu Sun, HaoJia Liu
wiley   +1 more source

Rate of convergence of attractors of reaction-diffusion equations with nonlinear boundary conditions

, 2020
This paper we study the rate of convergence of the asymptotic dynamics of reaction-diffusion equations with nonlinear Robin boundary conditions. We show how the rate of convergence of the global attractors can be affected by the variation of the ...
Bezerra, Flank David Moraes, Pires, Leonardo   +1 more
core  

Mortality trends and setbacks: global convergence or divergence?

, 2004
Health trends over much of the past century have been generally, and notably, positive throughout the world. In several regions, however, life expectancy has declined over the past 1-2 decades. This trend suggests that the expectation that emerged in the
McKee, Martin, McMichael, Anthony J, Shkolnikov, Vladimir, Valkonen, Tapani   +3 more
core   +1 more source

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman, Craig Blackstone, Reza Sadjadi   +2 more
wiley   +1 more source