Results 111 to 120 of about 4,277,769 (311)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Beyond borders: Building capacity and enhancing institutional resources for U.S.-Mexico virtual exchange initiatives

open access: yesJournal of Virtual Exchange
As the popularity of virtual exchange (VE) has increased worldwide in the wake of the COVID-19 pandemic, many higher education institutions are seeking the most efficient ways of building capacity for this practice.
Caroline E. Martins   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

All means all: An introduction to the 2020 Global Education Monitoring Report on inclusion. [PDF]

open access: yesProspects (Paris), 2020
Antoninis M   +14 more
europepmc   +1 more source

Education for Global Leadership: The Importance of International Studies and Foreign Language Education for U.S. Economic and National Security - Executive Summary [PDF]

open access: yes, 2006
Executive summary of "Education for Global Leadership: The Importance of International Studies and Foreign Language Education for U.S. Economic and National Security" report.

core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Guidelines for Transitional Education Plan Preparation [PDF]

open access: yes, 2016
The new global education agenda 2030 places strong emphasis on countries affected by adverse situations. It urges governments to put in place robust and responsive policies, strategies, and systems to ensure quality education in challenging contexts ...
Global Partnership for Education   +1 more
core   +1 more source

Defining global medical education needs

open access: yesAcademic Medicine, 1989
The graduates of medical education institutions should be, both in their numbers and in their acquired skills, appropriate to improving the health of the particular society they are intended to serve. Medical education should be tailored to deal with the diseases the physician is most apt to see--or at least apt to see in an academic medical center ...
openaire   +4 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

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