Results 81 to 90 of about 4,298,312 (312)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

IMPLEMENTATION OF GLOBAL COMPETENCY IN HIGHER EDUCATION

open access: yesNovìtnâ Osvìta, 2015
The article is devoted to the thorough characteristics of global competence as an important component of training young specialists. Globalization processes led to the irreversible changes in the modern society, opening the world borders and increasing ...
T. A. Anoshkova
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Global People landscaping study: intercultural effectiveness in global education partnerships [PDF]

open access: yes, 2009
The Context The Higher Education sector in the UK is experiencing a period of rapid and competitive internationalisation. The market for higher education, at undergraduate and post graduate levels, is now truly global: many potential students can make ...
Reid, S.   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Evaluating pedagogical approaches to enhance students’ comprehension in maritime English: The Norwegian case [PDF]

open access: yesKnowledge & Performance Management
This study aims to test and evaluate various pedagogical strategies that can improve students’ comprehension of Maritime English course materials and help them confidently participate in English-based assessments.
Viktoriia Koilo, Maksym Zaitsev
doaj   +1 more source

Continuing medical education: Global health, global learning [PDF]

open access: yesBMJ, 1998
CME—continuing medical education—has become an international discipline. Defined as any and all ways by which doctors learn after the formal completion of their training,1 CME is being shaped by several forces. Foremost among these are the globalisation of health2; cross disciplinary movements such as evidence based medicine; common trends in medical ...
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Reflexivity of participants of Football for Development project: experiential learning as delivery methodology of global education

open access: yesInternational Journal of Development Education and Global Learning
The power of sport to affect social change is widely acknowledged. However, little empirical research has explored the use of sport in engaging young people in global education.
doaj   +2 more sources

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