Results 31 to 40 of about 4,955,231 (255)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Representation of inner, outer and expanding circle varieties and cultures in global ELT textbooks

Asian-Pacific Journal of Second and Foreign Language Education, 2020
The rise of world Englishes has challenged the emphasis on native-speaker accents and cultures in English language teaching. This study aimed to investigate the representation of world Englishes and cultures in three global language teaching textbooks ...
Zia Tajeddin, Maryam Pakzadian
doaj   +1 more source

Global Englishes orientation questionnaire v1.0 [PDF]

, 2020
About the questionnaire The questionnaire was developed by a group of Global Englishes researchers in the Department of Education at The University of Oxford as a way to measure attitudes towards Global Englishes.
Briggs Baffoe-Djan, Jessica, Montakantiwong, Anuchaya, Rose, Heath, Funada, Natsuno   +3 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Language and literature in the information economy: the state of English, English and the state

Journal of the British Academy
The impact of colonialism and empire and then of transport, logistics, advertising, media, cinema, radio, tourism, and the internet extended the global reach of English.
Regenia Gagnier
doaj   +1 more source

World Englishes : Current trends and future directions

, 2017
This chapter sets out to review current trends in World Englishes (WE) research and publications. It does so through by first presenting an overview of current research in the field of world Englishes.
Bolton, Kingsley,
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

HIGH SCHOOL TEACHERS’ PERCEPTION AND ATTITUDE TOWARDS WORLD ENGLISHES: STUDY CASES IN LHOKSEUMAWE CITY, INDONESIA

Getsempena English Education Journal
This research explores the perceptions, attitudes, and teaching practices of senior high school English teachers in Lhokseumawe City, Aceh, Indonesia, regarding the concept of World Englishes (WE). As English continues to evolve as a global language, its
Hanif Hanif, Kurniawati Kurniawati, Dini Rizki, Dewi Kumala Sari   +3 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source