Results 131 to 140 of about 8,296,108 (395)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

On the global existence of solutions to the Prandtl's system

open access: yesAdvances in Mathematics, 2004
AbstractIn this paper we establish a global existence of weak solutions to the two-dimensional Prandtl's system for unsteady boundary layers in the class considered by Oleinik (J. Appl. Math. Mech. 30 (1966) 951) provided that the pressure is favourable.
Zhouping Xin, Liqun Zhang
openaire   +2 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

A global existence result for the anisotropic magnetohydrodynamical systems

open access: yes, 2016
We study an anisotropic system arising in magnetohydrodynamics (MHD) in the whole space R^3 , in the case where there are no diffusivity in the vertical direction and only a small diffusivity in the horizontal direction (of size $\epsilon$$\alpha$ with 0
Ngo, Van-Sang
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Second order p-evolution equations with critical nonlinearity

open access: yesBruno Pini Mathematical Analysis Seminar
In this paper, we study critical nonlinearities for global small data solutions to the plate equation and other second order p-evolution equations, possibly under the action of a noneffective dissipative term.
Marcello D'Abbicco, Giovanni Girardi
doaj   +1 more source

Existence and non-existence of global solutions for a discrete semilinear heat equation [PDF]

open access: yesarXiv, 2010
Existence of global solutions to initial value problems for a discrete analogue of a d-dimensional semilinear heat equation is investigated. We prove that a parameter \alpha in the partial difference equation plays exactly the same role as the parameter of nonlinearity does in the semilinear heat equation.
arxiv  

Quenching, global existence and blowup phenomena in heat transfer [PDF]

open access: yesarXiv, 2020
Basing on the relations between a system of ODE and a system of parabolic equations, we establish some general theories in heat transfer about quenching, global existence and blowup phenomena, obtain the conditions(even watershed) on f(u,v), g(u,v), a(x) and b(x) which let the solution be global existence, quench or blow up, and estimate the bounds for
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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