Results 91 to 100 of about 5,856,508 (299)

Financialisation: a 21st century commercial determinant of health equity

The Lancet Public Health
Summary: In 21st century capitalism, financial markets reign supreme. The elevation of investing, trading, and speculating as a way of making profit has shifted economic power towards institutional investors and enhanced the power of financial capital ...
Sharon Friel, ProfPhD, Ashley Schram, PhD, Nick Frank, PhD, Megan Arthur, PhD, Bel Townsend, PhD, Hridesh Gajurel, PhD   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Privatization of Global Governance

MGIMO Review of International Relations, 2017
Thomas Biersteker graduated from Chicago University (BF in Political Science) and MIT (MA in Political Science) and got PhD in Political Science in MIT as well. Later professor Biersteker lectured in Yale University (1976-1985), South Carolina University (1985-1992) and Brown University (1992-2006).
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Las cláusulas de elementos esenciales de los acuerdos comerciales de la UE: ¿Contribuye la política comercial de la UE a la protección de los Derechos Humanos?

Cuadernos Europeos de Deusto, 2015
Este artículo examina de una manera crítica la política europea de incluir cláusulas de ‘elementos esenciales’ en acuerdos comerciales, como principal medio para la realización del nexo comercio-derechos humano exigido por la obligación de la UE de ...
Nicolas Hachez
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Policy Integration for Sustainable Development through Multilateral Environmental Agreements: An Empirical Analysis, 2007-2016 [PDF]

, 2019
Over the past three decades, policy integration has become a key objective for guiding and harmonizing policies for sustainable development. Most recently, the 2015 Sustainable Development Goals have added new impetus to efforts of integrating competing ...
Global Sustainability Governance, Environmental Governance, Biermann, Frank, Kim, Rakhyun E., Azizi, Dona   +4 more
core   +1 more source

Forests and agroforestry as overlapping hotspots of woody species diversity and above-ground carbon storage in a Costa Rican landscape: a remote sensing analysis

Frontiers in Sustainable Food Systems
Tropical land-use change strongly affects biological diversity and carbon cycling at multiple spatial levels. Evidence for synergies between ecosystem services (ES), such as carbon storage and biodiversity, has been accumulating for natural and managed ...
Saskia Doherty, Achim Häger
doaj   +1 more source

Additional resource needs for viral hepatitis elimination through universal health coverage: projections in 67 low-income and middle-income countries, 2016–30

The Lancet Global Health, 2019
Summary: Background: The World Health Assembly calls for elimination of viral hepatitis as a public health threat by 2030 (ie, −90% incidence and −65% mortality).
David Tordrup, MSc, Yvan Hutin, MD, Karin Stenberg, MSc, Jeremy A Lauer, PhD, David W Hutton, PhD, Mehlika Toy, PhD, Nick Scott, PhD, Marc Bulterys, MD, Andrew Ball, MD, Gottfried Hirnschall, MD   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source