Results 101 to 110 of about 1,195,865 (301)

Global Governance Initiative Annual Report 2005 [PDF]

open access: yes, 2005
This is an annual report of the ...

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Politics of Subnational Decentralization in France, Brazil, and Italy

open access: yesJournal of Deliberative Democracy, 2013
Decentralized political institutions increasingly play a substantial role in the lives of people, implementing services deriving from influential (elected) bodies of governance, and influencing the relative degree of civil society access to policy-making.
Nick Vlahos
doaj   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Accountability in Global Governance [PDF]

open access: yes
human development ...
Ngaire Woods
core  

The Rockefeller Brothers Fund's Democratic Practice Global Governance Portfolio: Impact Assessment, 20102015 [PDF]

open access: yes, 2016
This report evaluates the progress of the Rockefeller Brothers Fund (RBF) Democratic Practice–Global Governance (DP-GG) portfolio in the context of the program-specific goal, strategies, and the RBF mission.
Kristen Hite, Melissa Shackleton Dann
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The Country Connector on Private Sector in Health: a global governance platform. [PDF]

open access: yesBMJ Glob Health, 2023
Clarke D   +6 more
europepmc   +1 more source

Taming governance with legality? Critical reflections upon global administrative law as small-c global constitutionalism [PDF]

open access: yes
The project of global administrative law has stood out from various efforts to tame global governance with the rule of law. By enhancing transparency and accountability, global administrative law is expected to improve the policy output of global ...
Kuo, Ming-Sung
core  

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