Results 131 to 140 of about 5,131,625 (338)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Global Governance

open access: yes, 2006
Die Sozialwissenschaften reden ganz selbstverständlich von Global Governance, obwohl es (noch) keinen Weltstaat und auch keine Weltregierung gibt. Dennoch hat sich eine Weltgesellschaft in nuce herausgebildet, die eigene, globale Formen der Regierung und der Selbststeuerung anstelle staatszentrierter politischer Steuerung hervorbringt.
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Halo effect and psychological contracts in student evaluations of teaching: a case study from a leading Chinese Liberal Arts University

open access: yesCogent Education
Student Evaluations of Teaching (SETs) have been a crucial tool worldwide for assessing faculty’s teaching effectiveness in universities. However, the validity of SETs measures has been widely questioned.
Enxi Jin, Xiaohua Jiang, Xiaqing Wang
doaj   +1 more source

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