Results 71 to 80 of about 7,037,374 (298)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Global longitudinal strain as a prognostic marker in cardiac resynchronisation therapy: A systematic review

, 2021
Purpose: Cardiac resynchronisation therapy (CRT) has proven mortality benefits for heart failure patients with moderate to severe systolic left ventricular dysfunction and evidence of a left bundle branch block. Determining responders to this therapy can
Tomlinson, S, Christian Hamilton-Craig, Chan, J, Nicholas D'Elia, Jonathan Chan, Mew, T, Appadurai, V, D'Elia, N, Vinesh Appadurai, Stephen Tomlinson, Hamilton-Craig, C, Thomas Mew, Scalia, GM, Gregory M. Scalia   +13 more
core   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Value of Myocardial Strain in Assessing Cardiac Masses: A Case Report

Methodist DeBakey Cardiovascular Journal
Transthoracic echocardiography and global longitudinal strain are pivotal in evaluating myocardial structure and function in cardio-oncology patients, but there are limited reports of using global longitudinal strain to identify intracardiac masses. This
Julianna West, Ihab Hamzeh, Jonathan You, Efstratios Koutroumpakis, Cezar Iliescu, Leslie Ynalvez, Hyeon-Ju Ali, Anita Deswal, Shaden Khalaf   +8 more
doaj   +1 more source

Global longitudinal strain, myocardial storage and hypertrophy in Fabry disease [PDF]

Heart, 2018
IntroductionDetecting early cardiac involvement in Fabry disease (FD) is important because therapy may alter disease progression. Cardiovascular magnetic resonance (CMR) can detect T1 lowering, representing myocardial sphingolipid storage. In many diseases, early mechanical dysfunction may be detected by abnormal global longitudinal strain (GLS).
Vijapurapu, R, Nordin, S, Baig, S, Liu, B, Rosmini, S, Augusto, J, Tchan, M, Hughes, DA, Geberhiwot, T, Moon, JC, Steeds, RP, Kozor, R   +11 more
openaire   +3 more sources

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Multilayer vs. global 2D-longitudinal strain in hypertrophic cardiomyopathy.

Archives of Cardiovascular Diseases Supplements, 2018
Introduction Hypertrophic cardiomyopathy (HCM) is a genetic heart disease defined by structural and functional abnormalities of the myocardium. HCM is characterized by systolic and diastolic dysfunction with major complications: sudden cardiac death and terminal heart failure. Altered left ventricular global longitudinal strain (LV GLS) is known to be
A. Coppin, A. Duva Pentiah, A. Coisne, H. Ridon, S. Mouton, P. De Groote, D. Montaigne   +6 more
openaire   +1 more source

Distinct Microstructural Characteristic Lengths Defining Notch Fatigue Crack Initiation and Propagation, and Defect Tolerance in Advanced Steels

Advanced Engineering Materials, EarlyView.
Schematic representation of modes of microcrack nucleation, growth and temporary arrestment at different boundaries, with the criteria for crack propagation in three scenarios: (1) large notch, (2) defect/small sharp notch, and (3) long crack. This work revisits and integrates results on the fatigue behavior of advanced bainitic steels (in particular ...
Lucia Morales‐Rivas
wiley   +1 more source

Left ventricular assessment in patients with mucopolysaccharidosis using conventional echocardiography and myocardial deformation by two‐dimensional speckle‐tracking method

Jornal de Pediatria (Versão em Português), 2019
Objective: Mucopolysaccharidosis is a rare genetic disease characterized by the intralysosomal deposition of glycosaminoglycans. Cardiovascular impairment is a common feature.
Mirela F.A. Andrade, Isabel Cristina B. Guimarães, Angelina X. Acosta, Emília Katiane E.A. Leão, Moisés I.G. Moreira, Carlos Maurício C. Mendes   +5 more
doaj   +3 more sources