Results 201 to 210 of about 115,200 (291)

A Label‐Free Hyperspectral Imaging Device for Ex Vivo Characterization and Grading of Meningioma Tissues

open access: yesJournal of Biophotonics, EarlyView.
HyperProbe1.1 enables rapid, label‐free biochemical mapping of freshly resected meningiomas. By quantifying endogenous biomarkers such as cytochrome c oxidase, hemoglobin derivatives, and lipids, the system reveals molecular signatures consistent with tumor grading and generates spatial maps that visualize metabolic and vascular heterogeneity across ...
Pietro Ricci   +13 more
wiley   +1 more source

Transforming healthcare with large language models: Current applications, challenges, and future directions—a literature review

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract AI‐based large language models (LLMs) have gradually made their way into various fields, transforming industries and changing the way we solve problems. LLMs have great potential in healthcare, where they can share the burden of data management, retrieval, and decision‐making.
Muhammad Umar   +11 more
wiley   +1 more source

Enhancing Study Design and Analysis of MR Imaging Markers Through Measurement Error Modeling

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Measurement error in imaging reduces statistical power and potentially biases parameter estimation, compromising study reliability. Purpose To introduce a dual data collection design (reliability and main datasets) to quantify measurement error and apply regression calibration to correct error‐prone imaging markers, thereby ...
Xiaofeng Wang   +8 more
wiley   +1 more source

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai   +6 more
wiley   +1 more source

Impact of Proton Pump Inhibitor Use on Outcomes Following Carotid Artery Stenting for Asymptomatic Carotid Stenosis: A Population‐Based Cohort Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Carotid artery stenting (CAS) is an effective treatment for carotid stenosis. Proton‐pump inhibitors (PPIs) are commonly prescribed in the general population. However, the impact of PPI use on outcomes following CAS remains unknown. This study investigated the impact of PPI use on CAS using a retrospective, matched‐cohort analysis from the ...
Chia‐En Wong   +7 more
wiley   +1 more source

Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing‐off Symptoms

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) often involves motor fluctuations and dyskinesia, which are difficult to manage with medication alone. Conventional deep brain stimulation (cDBS) effectively alleviates symptoms but has limitations, including the challenge of balancing therapeutic effects against potential side effects, as well as limited ...
Takuto Emura   +11 more
wiley   +1 more source

Novel Neurotechnologies:Intervening in the Brain [PDF]

open access: yes, 2013
Baldwin, Thomas   +10 more
core  

Investigating Sleep Concerns in Cervical Dystonia

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Heterogenous, small cohorts, and co‐occurrence of pain and psychiatric burden complicate understanding of sleep in dystonia. Objective To investigate sleep concerns in cervical dystonia (CD). Methods Longitudinal data from CD‐PROBE on subjects who were toxin‐naïve, new to practice, or without injections for at least 16 weeks were ...
Abhimanyu Mahajan   +2 more
wiley   +1 more source

Clinical and Radiological Evolution of Idiopathic Normal Pressure Hydrocephalus: A Critical Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) remains poorly understood. While it is commonly accepted that iNPH has an insidious onset, little is known about its preclinical and early stages and its development over time.
David Campo‐Caballero   +6 more
wiley   +1 more source

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