Results 61 to 70 of about 2,964,939 (305)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
IntroductionGlobal health education (GHE) is expected to prepare professionals to address complex, interlinked global challenges. However, current GHE structures often reflect persistent power asymmetries between the Global North and South, limiting the ...
Samraj Singh Bhullar +7 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms affecting the overturning response in global warming simulations [PDF]
Climate models used to produce global warming scenarios exhibit widely diverging responses of the thermohaline circulation (THC). To investigate the mechanisms responsible for this variability, a regional Atlantic Ocean model driven with forcing ...
Schweckendiek, Ulf, Willebrand, Jürgen
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Towards a UK local government reform Act of 2015: improving public sector performance for 2025 [PDF]
This paper proposes a three tiered governance structure to rebalance local government within the United Kingdom. The introduction of a North of England assembly is proposed to rebalance the North / South divide.
Kakabadse, Nada K, Khan, N
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The concept of ‘South-South cooperation,’ which dates back to the Cold War, has received a new impetus in the 21st century. In this context, China occupies a unique place, as its very identification with the Global South under modern conditions is a ...
I. I. Arsentyeva
doaj +1 more source
Chinese and North American Culture: a New Perspective in Linguistics Studies [PDF]
We explored the two cultures in the two countries. There has been discussed on Chinese culture and North American culture. Chinese language, ceramics, architecture, music, dance, literature, martial arts, cuisine, visual arts, philosophy, business ...
Huan, C. Y. (Cheng), Li, Z. X. (Ziang)
core
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source

