Results 71 to 80 of about 2,964,939 (305)

Integrating global perspectives in biomedical science education: the role of project-based learning in addressing Western-centric paradigms and enhancing student preparedness for global health challenges

Frontiers in Education
Biomedical Sciences education has traditionally focused on Western paradigms, often overlooking the health challenges faced in less economically developed countries.
Joanne Daniella Lalujan, Md Zahidul I. Pranjol   +1 more
doaj   +1 more source

Global Models and North-South Relations [PDF]

International Political Science Review, 1990
Global modeling has evolved remarkably in the last two decades. Such evolution led it to perform today's role as an experimental laboratory for the social sciences, and particularly for applications to policy planning. Two of the most interesting applications to policy are to resource economics and to economic models of North-South relations, i.e ...
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A large terrestrial source of methyl iodide [PDF]

, 2007
We have identified terrestrial sources of methyl iodide (CH3I) and assessed their importance in its atmospheric budget using a synthesis of field observations.
Blake, DR, Mao, H, Sive, BC, Talbot, R, Varner, RK, Wingenter, OW   +5 more
core   +4 more sources

Factors relating to the attraction of talented early career academics in South African higher education institutions

SA Journal of Human Resource Management, 2018
Orientation: South African higher education institutions (HEIs) are facing significant challenges in attracting talents to academic positions. Research purpose: The main objective of this research was to determine factors that will attract early career ...
Dorcas L. Lesenyeho, Nicolene E. Barkhuizen, Nico E. Schutte   +2 more
doaj   +1 more source

Is Emission Trading Beneficial? [PDF]

We develop a two-country (North and South), two-good, general equilibrium model of international trade in goods and explore the effects of domestic and international emission trading under free trade in goods.
Ishikawa, Jota, Kiyono, Kazuharu, Yomogida, Morihiro   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Migración haitiana de tránsito: la ruta migratoria por Santiago de Chile y la aspiración de llegar hacia el norte global

Antípoda: Revista de Antropología y Arqueología
This article examines Haitian migration to Santiago, Chile, with a particular focus on the primary transit routes taken by this group and the challenges they face upon arrival.
Lissette Madriaga-Parra, Nicolás Gissi-Barbieri   +1 more
doaj   +1 more source

Building capacity for Public Health 3.0: introducing implementation science into an MPH curriculum

Implementation Science, 2019
Background Many public health programs fail because of an inability to implement tested interventions in diverse, complex settings. The field of implementation science is engaged in developing strategies for successful implementation, but current ...
Rohit Ramaswamy, Joe Mosnier, Kristin Reed, Byron J. Powell, Anna P. Schenck   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source