Results 71 to 80 of about 8,929,107 (285)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

W49A North: Global or Local or No Collapse?

open access: yesThe Astrophysical Journal Supplement Series, 2004
42 pages, 27 figures, accepted for publication in the ApJS August 2004, v153 ...
Williams, John A.   +2 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adopting a Universal Mandate on Platform Work: Balancing Contrasting Realities

open access: yesTilburg Law Review
The challenges that present-day globalization poses in setting international labour standards are not uncharted. The conflict between the role of global considerations, on the one hand, and national and local dimensions, on the other, is one well-known ...
Juliana Londoño Polo
doaj   +1 more source

Associations between placental CpG methylation of metastable epialleles and childhood body mass index across ages one, two and ten in the Extremely Low Gestational Age Newborns (ELGAN) cohort

open access: yesEpigenetics, 2019
The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that in utero and early life conditions can disrupt normal fetal development and program susceptibility to later-life disease.
Jeliyah Clark   +6 more
doaj   +1 more source

Global Models and North-South Relations [PDF]

open access: yesInternational Political Science Review, 1990
Global modeling has evolved remarkably in the last two decades. Such evolution led it to perform today's role as an experimental laboratory for the social sciences, and particularly for applications to policy planning. Two of the most interesting applications to policy are to resource economics and to economic models of North-South relations, i.e., the
openaire   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Displacing Northern Dominant Criminological Discourse: The Importation of Southern Criminology into Criminological Literature and Its Implications

open access: yesContemporary Challenges
Through a carefully selected set of criminological case studies from both the Global North and the Global South, this article takes on a critical approach on how hegemonic Northern criminological theories have fallen short in their attempts at ...
Yu Jie Ong
doaj   +1 more source

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