Results 91 to 100 of about 7,124,818 (299)

Integrating global perspectives in biomedical science education: the role of project-based learning in addressing Western-centric paradigms and enhancing student preparedness for global health challenges

open access: yesFrontiers in Education
Biomedical Sciences education has traditionally focused on Western paradigms, often overlooking the health challenges faced in less economically developed countries.
Joanne Daniella Lalujan   +1 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

From global north to south: governing contaminants of emerging concern in water systems

open access: yesEnvironmental Research Letters
Contaminants of emerging concern (CECs), notably per- and polyfluoroalkyl substances (PFAS), pharmaceuticals, and microplastics (MPs), are increasingly detected in water systems, posing growing risks to ecosystems, human health, and socio-economic ...
Nhlanhla Hlongwa   +4 more
doaj   +1 more source

Factors relating to the attraction of talented early career academics in South African higher education institutions

open access: yesSA Journal of Human Resource Management, 2018
Orientation: South African higher education institutions (HEIs) are facing significant challenges in attracting talents to academic positions. Research purpose: The main objective of this research was to determine factors that will attract early career ...
Dorcas L. Lesenyeho   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Opportunities and barriers in diversified farming and the use of agroecological principles in the Global North – The experiences of Danish biodynamic farmers

open access: yesAgroecology and Sustainable Food Systems, 2020
Diversification through agroecological principles may maintain and stabilize yields in an increasingly more unpredictable climate, including market price fluctuations, as well as preserve and enhance the threatened natural resource base and the ...
Ane Kirstine Aare   +3 more
semanticscholar   +1 more source

Migración haitiana de tránsito: la ruta migratoria por Santiago de Chile y la aspiración de llegar hacia el norte global

open access: yesAntípoda: Revista de Antropología y Arqueología
This article examines Haitian migration to Santiago, Chile, with a particular focus on the primary transit routes taken by this group and the challenges they face upon arrival.
Lissette Madriaga-Parra   +1 more
doaj   +1 more source

Building capacity for Public Health 3.0: introducing implementation science into an MPH curriculum

open access: yesImplementation Science, 2019
Background Many public health programs fail because of an inability to implement tested interventions in diverse, complex settings. The field of implementation science is engaged in developing strategies for successful implementation, but current ...
Rohit Ramaswamy   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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