Results 61 to 70 of about 5,020,641 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Globally optimal regions and boundaries [PDF]

open access: yesProceedings of the Seventh IEEE International Conference on Computer Vision, 1999
We propose a new form of energy functional for the segmentation of regions in images, and an efficient method for finding its global optima. The energy can have contributions from both the region and its boundary, thus combining the best features of region- and boundary-based approaches to segmentation. By transforming the region energy into a boundary
Ian Jermyn, Hiroshi Ishikawa 0002
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dialectal variation in german 3-verb clusters : a surface-oriented optimality theoretic account [PDF]

open access: yes, 2004
We present data from an empirical investigation on the dialectal variation in the syntax of German 3-verb clusters, consisting of a temporal auxiliary, a modal verb, and a predicative verb. The ordering possibilities vary greatly among the dialects. Some
Schmid, Tanja   +2 more
core   +1 more source

Feedback Minimum Principle for Quasi-Optimal Processes of Terminally-Constrained Control Problems

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2017
In a series of previous works, we derived nonlocal necessary optimality conditions for free-endpoint problems. These conditions strengthen the Maximum Principle and are unified under the name “feedback minimum principle”.
V.A. Dykhta
doaj   +1 more source

Optimal control problem for 3D micropolar fluid equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2020
In this paper we study an optimal control problem related to strong solutions of 3D micropolar fluid equations. We deduce the existence of a global optimal solution with distributed control and, using a Lagrange multipliers theorem, we derive first-order
Exequiel Mallea-Zepeda, Luis Medina
doaj   +1 more source

On nonsmooth mathematical programs with equilibrium constraints using generalized convexity [PDF]

open access: yesYugoslav Journal of Operations Research, 2019
In this paper, we derive the sufficient condition for global optimality for a nonsmooth mathematical program with equilibrium constraints involving generalized invexity.
Joshi Bhuwan Chandra   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Global optimality conditions for mixed integer nonlinear programming problems

open access: yes四川大学学报. 自然科学版, 2017
In recent years, the application of mixed integer nonlinear programming problem has been extremely active and very extensive. In this paper, some necessary conditions for a given global minimizer applied to mixed integer nonlinear programming problem ...
QUAN Jing, LI Guo-Quan
doaj  

Optimality Conditions Characterizing Approximate Solutions for DC Composite Programs

open access: yesJournal of Mathematics
This paper concerns DC composite optimization problems with conic constraints. By virtue of epigraph of conjugate functions, we introduce some new regularity conditions.
Gang Li, Qiqiong Chen
doaj   +1 more source

Home - About - Disclaimer - Privacy