Results 61 to 70 of about 5,020,641 (311)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Globally optimal regions and boundaries [PDF]
We propose a new form of energy functional for the segmentation of regions in images, and an efficient method for finding its global optima. The energy can have contributions from both the region and its boundary, thus combining the best features of region- and boundary-based approaches to segmentation. By transforming the region energy into a boundary
Ian Jermyn, Hiroshi Ishikawa 0002
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dialectal variation in german 3-verb clusters : a surface-oriented optimality theoretic account [PDF]
We present data from an empirical investigation on the dialectal variation in the syntax of German 3-verb clusters, consisting of a temporal auxiliary, a modal verb, and a predicative verb. The ordering possibilities vary greatly among the dialects. Some
Schmid, Tanja +2 more
core +1 more source
Feedback Minimum Principle for Quasi-Optimal Processes of Terminally-Constrained Control Problems
In a series of previous works, we derived nonlocal necessary optimality conditions for free-endpoint problems. These conditions strengthen the Maximum Principle and are unified under the name “feedback minimum principle”.
V.A. Dykhta
doaj +1 more source
Optimal control problem for 3D micropolar fluid equations
In this paper we study an optimal control problem related to strong solutions of 3D micropolar fluid equations. We deduce the existence of a global optimal solution with distributed control and, using a Lagrange multipliers theorem, we derive first-order
Exequiel Mallea-Zepeda, Luis Medina
doaj +1 more source
On nonsmooth mathematical programs with equilibrium constraints using generalized convexity [PDF]
In this paper, we derive the sufficient condition for global optimality for a nonsmooth mathematical program with equilibrium constraints involving generalized invexity.
Joshi Bhuwan Chandra +2 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Global optimality conditions for mixed integer nonlinear programming problems
In recent years, the application of mixed integer nonlinear programming problem has been extremely active and very extensive. In this paper, some necessary conditions for a given global minimizer applied to mixed integer nonlinear programming problem ...
QUAN Jing, LI Guo-Quan
doaj
Optimality Conditions Characterizing Approximate Solutions for DC Composite Programs
This paper concerns DC composite optimization problems with conic constraints. By virtue of epigraph of conjugate functions, we introduce some new regularity conditions.
Gang Li, Qiqiong Chen
doaj +1 more source

