Results 81 to 90 of about 6,868 (254)
A Geometric Approach to Global Optimization
Journal of Global Optimization, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nickel, Stefan, Schöbel, Anita
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Sufficient conditions for global optimality of semidefinite optimization
, 2012 In this article, by using the Lagrangian function, we investigate the sufficient global optimality conditions for a class of semi-definite optimization problems, where the objective function are general nonlinear, the variables are mixed integers subject
Wu, Zhiyou +7 more
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Optimality Conditions Characterizing Approximate Solutions for DC Composite Programs
Journal of MathematicsThis paper concerns DC composite optimization problems with conic constraints. By virtue of epigraph of conjugate functions, we introduce some new regularity conditions.
Gang Li, Qiqiong Chen
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Optimization of the standard genetic code according to three codon positions using an evolutionary algorithm. [PDF]
PLoS ONE, 2018 Many biological systems are typically examined from the point of view of adaptation to certain conditions or requirements. One such system is the standard genetic code (SGC), which generally minimizes the cost of amino acid replacements resulting from ...
Paweł Błażej +3 more
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Global Optimization of Robotic Grasps
Robotics: Science and Systems VII, 2011 This paper presents a procedure to optimize the quality of robotic grasps for objects that need to be held and manipulated in a specific way, characterized by a number of tight contact constraints. The main difficulties of the problem include that the set of feasible grasps is a manifold implicitly defined by a system of non-linear equations, the high ...
Rosales Gallegos, Carlos +2 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Partial Differential Equations in Applied MathematicsIn this paper, we present a Wolfe-type dual model containing the Caputo-Fabrizio fractional derivative, weak and strong duality results, number of Kuhn-Tucker type sufficient optimality conditions and duality results for variational problems (VPs) with ...
Ved Prakash Dubey +3 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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