Results 91 to 100 of about 5,020,641 (311)
A Randomized Algorithm for Optimal PID Controllers
Algorithms, 2018 A randomized algorithm is suggested for the syntheses of optimal PID controllers for MIMO coupled systems, where the optimality is with respect to the H ∞ -norm, the H 2 -norm and the LQR functional, with possible system-performance ...
Yossi Peretz
doaj +1 more source
A Geometric Approach to Global Optimization
Journal of Global Optimization, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nickel, Stefan, Schöbel, Anita
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
ORTHOGONAL TRACE-SUM MAXIMIZATION: APPLICATIONS, LOCAL ALGORITHMS, AND GLOBAL OPTIMALITY. [PDF]
SIAM J Matrix Anal Appl, 2021 Won JH, Zhou H, Lange K.
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Population Structures in Russia: Optimality and Dependence on Parameters of Global Evolution
REGION, 2016 The paper is devoted to analytical investigation of the division of geographical space into urban and rural areas with application to Russia. Yegorov (2005, 2006, 2009) has suggested the role of population density on economics.
Yuri Yegorov
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Global Optimization of Robotic Grasps
Robotics: Science and Systems VII, 2011 This paper presents a procedure to optimize the quality of robotic grasps for objects that need to be held and manipulated in a specific way, characterized by a number of tight contact constraints. The main difficulties of the problem include that the set of feasible grasps is a manifold implicitly defined by a system of non-linear equations, the high ...
Rosales Gallegos, Carlos +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Invasion Percolation and Global Optimization
Physical Review Letters, 1996 4 pages, 3 Postscript figures avaliable from alb@nd.edu ...
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source