Results 61 to 70 of about 30,043 (263)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Structured Singular Value Control With General Two‐Degree‐of‐Freedom Feedback Loop Factorisation for Single‐Input Single‐Output Systems

The Journal of Engineering
General two‐degree‐of‐freedom feedback loop factorisation for single‐input single‐output systems applied to oscillating plants with time delay, periodic changes of the controlled plant parameters and astatism using the D‐K iteration and algebraic ...
Marek Dlapa
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

IAROA: An Enhanced Attraction–Repulsion Optimisation Algorithm Fusing Multiple Strategies for Mechanical Optimisation Design

Biomimetics
Attraction–Repulsion Optimisation Algorithm (AROA) is a newly proposed metaheuristic algorithm for solving global optimisation problems, which simulates the equilibrium relating to the attraction and repulsion phenomenon that occurs in the natural world,
Na Zhang, Ziwei Jiang, Gang Hu, Abdelazim G. Hussien   +3 more
doaj   +1 more source

Minimising disparity in distribution for unsupervised domain adaptation by preserving the local spatial arrangement of data

IET Computer Vision, 2016
Domain adaptation is used for machine learning tasks, when the distribution of the training (obtained from source domain) set differs from that of the testing (referred as target domain) set.
Suranjana Samanta, Sukhendu Das
doaj   +1 more source

An adaptive Cuckoo search algorithm for optimisation

Applied Computing and Informatics, 2018
Cuckoo search is one of many nature-inspired algorithms used extensively to solve optimisation problems in different fields of engineering. It is a very effective in solving global optimisation because it is able to maintain balance between local and ...
M. Mareli, B. Twala
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

A real-world industrial case study: application of the bees algorithm to the force optımisation of a mobile crane hydraulic cylinder

Cogent Engineering
This paper presents a real-world industrial case study on the force optimisation of a hydraulic cylinder in a mobile knuckle boom crane using the Bees Algorithm (BA). The primary objective is to minimize the maximum hydraulic cylinder force corresponding
Mete Kalyoncu, Abdullah Erdemir
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Pareto-like sequential sampling heuristic for global optimisation. [PDF]

Soft comput, 2021
Shaqfa M, Beyer K.
europepmc   +1 more source