Results 61 to 70 of about 1,449,938 (284)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Electrical Storm Optimization (ESO) Algorithm: Theoretical Foundations, Analysis, and Application to Engineering Problems

open access: yesMachine Learning and Knowledge Extraction
The electrical storm optimization (ESO) algorithm, inspired by the dynamic nature of electrical storms, is a novel population-based metaheuristic that employs three dynamically adjusted parameters: field resistance, field intensity, and field ...
Manuel Soto Calvo, Han Soo Lee
doaj   +1 more source

Hole Filling for View Synthesis Using Depth Guided Global Optimization

open access: yesIEEE Access, 2018
View synthesis is an effective way to generate multi-view contents from a limited number of views, and can be utilized for 2-D-to-3-D video conversion, multi-view video compression, and virtual reality. In the view synthesis techniques, depth-image-based
Guibo Luo, Yuesheng Zhu
doaj   +1 more source

Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]

open access: yes, 2009
This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Bates, D.G.   +4 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

An Enhanced Tree-Seed Algorithm for Function Optimization and Production Optimization

open access: yesBiomimetics
As the fields of engineering, energy, and geology become increasingly complex, decision makers face escalating challenges that require skilled solutions to meet practical production needs.
Qingan Zhou   +4 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

An Improved Artificial Bee Colony Algorithm With Fitness-Based Information

open access: yesIEEE Access, 2019
Artificial bee colony (ABC) algorithm is widely known for its distinguished exploration ability. However, its exploitation ability is relatively poor.
Wan-Li Xiang   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Adaptive Tasmanian Devil Optimizer for Global Optimization and Application in Wireless Sensor Network Deployment

open access: yesIEEE Access
The Tasmanian Devil Optimization (TDO) algorithm, a recently popular metaheuristic algorithm, exhibits issues such as slow convergence, low precision, and susceptibility to getting stuck in local optima when applied to practical problems.
Wei Wang, Lixin Lyu
doaj   +1 more source

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