Results 51 to 60 of about 1,342,058 (331)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The United Nations and Global Public Goods: Historical Contributions and Future Challenges.

Revue Internationale de Politique de Développement, 2012
Published by Palgrave MacmillanThis chapter explores the thesis that the United Nations’ (UN) most important contribution to the production of global public goods has been its role in creating the space and capacity to generate shared values.
Bruce Jenks
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Globalization and Global Public Goods [PDF]

, 2011
Everyday, the importance of global public goods (GPGs) is increasing in the globalization process. GPGs are public goods with benefits or costs (peace, crime, terrorism, disease etc.) that extend across countries and regions, across rich and poor population groups, and even across generations.
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Global Public Economics: Public Goods and Externalities [PDF]

Économie publique/Public economics, 2007
Cet article etend l’analyse normative des biens publics et des externalites a un environnement international. La premiere partie considere l’allocation optimale d’un bien public glo­bal. Le caractere desirable de l’efficacite productive globale depend de l’existence de transferts forfaitaires internatio­naux.
openaire   +3 more sources

Open Knowledge Resources for Higher Education: Scholarly Publications, Course Materials, Academic Software [PDF]

, 2006
This paper will explain why electronic knowledge resources in academia cannot only be regarded as private commodities, but also as public goods. After sketching a concept of public goods for a postnational, global society, three types of electronic ...
Thomas Pfeffer
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Genetically modified foods as global public goods

Suma de Negocios, 2014
"Genetically modified (GM) food has become very important in the field of research, as a result of its expansion in recent decades. As the right to food is a human right, it cannot be left in the hands of private sector developments exclusively, due to ...
Susana Herrero Olarte
doaj