Results 61 to 70 of about 892,070 (301)
Cyberspace: Global Public Goods? [PDF]
Acta Oeconomica Pragensia, 2018 Cyberspace has become an indispensable part of our everyday lives. Due to the Internet of Things, it has permeated the whole of society. Nevertheless, cyberspace on its own still tends to be neglected in academia, especially in social sciences. This article aims to contribute to the debate over whether cyberspace may be labelled as global public goods.
openaire +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
As ruralidades nas políticas globais
Desenvolvimento e Meio Ambiente, 2015 This paper aims at providing a scheme, theoretical and historical as well, of contemporaneous changes of rural societies by referring to the specific experience of west-European countries. This concept of rural – that opened the field of rural sociology –
Marc Mormont
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Global public goods and health: taking the agenda forward
Bulletin of the World Health Organization, 2001 We examined recent special health initiatives to control HIV/AIDS, malaria, and tuberculosis, and make four policy recommendations for improving the sustainability of such initiatives. First, international cooperation on health should be seen as an issue
Kaul Inge, Faust Michael
doaj
Human Rights and Global Public Goods:The Sound of One Hand Clapping? [PDF]
, 2015 Each operating in a presumptively general or universal register, \u27public goods and human rights are among the most popular and visible contemporary carriers of ideas of global law and governance and are therefore prime sources for any broader ...
Walker, Neil
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Legitimizing Private Actors in Global Governance: From Performance to Performativity
Politics and Governance, 2017 Global governance is frequently criticised because of major legitimacy deficits, including lack of public accountability and democratic control. Within this context, questions about the legitimacy of non-state governance actors, such as non-governmental ...
Elke Krahmann
doaj +1 more source