Results 121 to 130 of about 2,615,111 (244)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
High temperature sensitivity of monoterpene emissions from global vegetation
Communications Earth & EnvironmentTerrestrial vegetation emits vast amounts of monoterpenes into the atmosphere, influencing ecological interactions and atmospheric chemistry. Global emissions are simulated as a function of temperature with a fixed exponential relationship (β coefficient)
Efstratios Bourtsoukidis +12 more
doaj +1 more source
Global sensitivity analysis in epidemiological modeling. [PDF]
Eur J Oper Res, 2023 Lu X, Borgonovo E.
europepmc +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Global Sensitivity Analysis of Background Life Cycle Inventories. [PDF]
Environ Sci Technol, 2022 Kim A, Mutel CL, Froemelt A, Hellweg S.
europepmc +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Analysis of Hepatic Lipid Metabolism Model: Simulation and Non-Stationary Global Sensitivity Analysis. [PDF]
Nutrients, 2022 Kosić M +5 more
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Global sensitivity analysis to enhance the transparency and rigour of energy system optimisation modelling. [PDF]
Open Res Eur, 2023 Usher W, Barnes T, Moksnes N, Niet T.
europepmc +1 more source