Results 141 to 150 of about 938,399 (265)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Correction: An efficient and flexible framework for inferring global sensitivity of agent-based model parameters. [PDF]

PLoS Comput Biol
Bergman DR, Jackson T, Jain HV, Norton KA.   +3 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Multi-objective global sensitivity analysis of shipborne equipment based on AGPSO-CNN-BiLSTM-attention. [PDF]

Sci Rep
Wu S, Yan M, Zhang L, Feng L, Yang N, Liu H.   +5 more
europepmc   +1 more source

Global Sensitivity Analysis in Life-Cycle Assessment of Early-Stage Technology using Detailed Process Simulation: Application to Dialkylimidazolium Ionic Liquid Production. [PDF]

ACS Sustain Chem Eng, 2023
Baaqel HA, Bernardi A, Hallett JP, Guillén-Gosálbez G, Chachuat B.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

An efficient and flexible framework for inferring global sensitivity of agent-based model parameters. [PDF]

PLoS Comput Biol
Bergman DR, Jackson T, Jain HV, Norton KA.   +3 more
europepmc   +1 more source

Global Sensitivity Analysis with Mixtures: A Generalized Functional ANOVA Approach. [PDF]

Risk Anal, 2022
Borgonovo E, Li G, Barr J, Plischke E, Rabitz H.   +4 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Global Sensitivity Analyses of the APSIM-Wheat Model at Different Soil Moisture Levels. [PDF]

Plants (Basel)
Zhang Y, Ai P, Ma Y, Fu Q, Ma X.
europepmc   +1 more source