Results 51 to 60 of about 913,957 (308)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Design of an integral sliding mode controller for reducing CO2 emissions in the transport sector to control global warming

Scientific Reports
Carbon dioxide (CO2) is the significant contributor to greenhouse gases and plays a crucial role in the greenhouse effect and climate change. The primary source of CO2 emissions is fossil fuel combustion, basically due to human activities and ...
Abid Mehmood, Mohsan Hassan, Pita Donald, Mohammed M. A. Almazah   +3 more
doaj   +1 more source

On the mathematical modeling of schistosomiasis transmission dynamics with heterogeneous intermediate host

Frontiers in Applied Mathematics and Statistics, 2022
Schistosomiasis is a neglected disease affecting almost every region of the world, with its endemicity mainly experience in sub-Saharan Africa. It remains difficult to eradicate due to heterogeneity associated with its transmission mode.
Chinwendu E. Madubueze, Z. Chazuka, I. O. Onwubuya, F. Fatmawati, C. W. Chukwu   +4 more
doaj   +1 more source

Global sensitivity analysis of the GRNN model.

, 2022
Global sensitivity analysis of the GRNN model.
Qingqing Yang (1628146), Yuan Chen (9740), Zeyu Zhang (549929), Fubing Zha (10798232), Mingchao Zhou (3874408), Jianjun Long (6736796), Sheng Qu (5447120), Jiehui Li (139490), Yulong Wang (747450), Shengxiu Jiao (12530676), Kaiwen Xue (10660073)   +10 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Global Sensitivity Analysis and Uncertainty Quantification for Simulated Atrial Electrocardiograms

Metrology, 2022
The numerical modeling of cardiac electrophysiology has reached a mature and advanced state that allows for quantitative modeling of many clinically relevant processes.
Benjamin Winkler, Claudia Nagel, Nando Farchmin, Sebastian Heidenreich, Axel Loewe, Olaf Dössel, Markus Bär   +6 more
doaj   +1 more source

Efficient Global and Local Force Calculations Based on Continuum Sensitivity Analysis

, 2006
Equations derived from continuum design sensitivity analysis are successfully applied to calculation of both total force and force distributions. The proposed method has several advantages over the traditional approaches based on Maxwell Stress Tensor or
Lowther, D.A., Kim, D.H., Dong-hun Kim, Sykulski, J.K., Jan K. Sykulski, David A. Lowther   +5 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Global Sensitivity Analysis Method Based on Support Vector Machine

Hangkong gongcheng jinzhan, 2018
Aiming at the difficulties of implicit limit state function and high-computational cost in structural sensitivity analysis, a new method is proposed for structural global sensitivity analysis which is based on support vector machine(SVM) method and Monte
Zhang Hang, Li Hongshuang
doaj   +1 more source