Results 61 to 70 of about 2,456,167 (285)

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Global Sensitivity Analysis of a Microbial Fuel Cell Model

International Journal of Electrochemical Science, 2019
The global sensitivity method based on variance was applied to the microbial fuel cell (MFC) field for the first time here. The purpose of this study was to expound how the global sensitivity method can be used in the mathematical model of MFC and to ...
Yankai Yin, Chengcai Fu, Fengying Ma
doaj   +1 more source

Global Sensitivity Analysis and Uncertainty Quantification for Simulated Atrial Electrocardiograms

Metrology, 2022
The numerical modeling of cardiac electrophysiology has reached a mature and advanced state that allows for quantitative modeling of many clinically relevant processes.
Benjamin Winkler, Claudia Nagel, Nando Farchmin, Sebastian Heidenreich, Axel Loewe, Olaf Dössel, Markus Bär   +6 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Global Sensitivity Analysis Method Based on Support Vector Machine

Hangkong gongcheng jinzhan, 2018
Aiming at the difficulties of implicit limit state function and high-computational cost in structural sensitivity analysis, a new method is proposed for structural global sensitivity analysis which is based on support vector machine(SVM) method and Monte
Zhang Hang, Li Hongshuang
doaj   +1 more source

Sensitivity Analysis of the Global Response of Flexible Rockfall Barriers

Geosciences, 2022
Protection barriers against the fall of boulders and rocks are structures with non-linear mechanical behaviour that make the study particularly complex.
Cyril Douthe, Chloé Girardon, Romain Boulaud   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Workflow for Global Sensitivity Analysis of PBPK Models

Frontiers in Pharmacology, 2011
Physiologically based pharmacokinetic models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can ...
Kevin eMcNally, Richard eCotton, George D Loizou   +2 more
doaj   +1 more source