Results 91 to 100 of about 8,988,058 (267)

Analyticity and Existence of the Keller–Segel–Navier–Stokes Equations in Critical Besov Spaces

open access: yesAdvanced Nonlinear Studies, 2018
This paper deals with the Cauchy problem to the Keller–Segel model coupled with the incompressible 3-D Navier–Stokes equations. Based on so-called Gevrey regularity estimates, which are motivated by the works of Foias and Temam [20], we prove that the ...
Yang Minghua, Fu Zunwei, Liu Suying
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Global existence and blow-up of solutions for parabolic systems with nonlinear nonlocal boundary conditions

open access: yesElectronic Journal of Differential Equations, 2013
In this article we study a nonlinear parabolic system with nonlinear nonlocal boundary conditions. We prove the uniqueness of the solutions and establish the conditions for global solutions and non-global solutions.
Zhou Sen, Zuodong Yang
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Existence and continuation of solutions for Caputo type fractional differential equations

open access: yesElectronic Journal of Differential Equations, 2016
In this article, we consider a fractional differential equation (FDE) with Caputo derivative and study the existence and continuation of its solution. Firstly, we prove a theorem on the existence of local solutions.
Changpin Li, Shahzad Sarwar
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The National Global Change Research Plan 2012-2021: A Triennial Update

open access: yes, 2017
This report is the third triennial update of the National Global Change Research Plan based on scientific research from 13 Federal agencies. The purpose of each update is to "advance science, inform decisions, conduct...assessments" and communicate ...
U.S. Global Change Research Program
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Secret level valuation method of BLP model based on some application properties

open access: yesTongxin xuebao, 2013
According to the access attribute properties between subjects and objects in the information system,a viable method of the BLP model secret level valuation was given,and two merging conditions were put forward.The mathematical model of subject-object ...
Chan DONG   +3 more
doaj  

Global Warming: A Titanic Problem [PDF]

open access: yes, 2012
Global warming is one of those areas of science that gets all sorts of people exited Though a few ask for more and more evidence that global environmental change is taking place most accept that human activities are causing changes quite unlike any ...
Dr. Md. Zulfequar Ahmad Khan
core  

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