Results 81 to 90 of about 798,781 (261)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Boundedness and global solvability for a chemotaxis-haptotaxis model with p-Laplacian diffusion
Electronic Journal of Differential Equations, 2020 We consider a chemotaxis-haptotaxis system with $p$-Laplacian diffusion in three dimensional bounded domains. It is asserted that for any p>2, under the appropriate assumptions, the chemotaxis-haptotaxis system admits a global bounded weak ...
Changchun Liu, Pingping Li
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Existence of global solutions for a predator-prey model with cross-diffusion
Electronic Journal of Differential Equations, 2008 In this article, we prove the existence of global classical solutions for a prey-predator model when the space dimension ...
Shenghu Xu
doaj
Approximation to the global solution of generalized Zakharov equations in R 2. [PDF]
J Inequal Appl, 2018 You S.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Existence of global solutions for systems of second-order differential equations with p-Laplacian
Electronic Journal of Differential Equations, 2007 We obtain sufficient conditions for the existence of global solutions for the systems of differential equations $$ ig(A(t)Phi_p(y')ig)' + B(t)g(y') + R(t)f(y) = e(t), $$ where $Phi_p(y')$ is the multidimensional p-Laplacian.
Eva Pekarkova, Milan Medved
doaj
Towards the Prediction of Global Solution State Properties for Hydrogen Bonded, Self-Associating Amphiphiles. [PDF]
Chemistry, 2018 White LJ +7 more
europepmc +1 more source