Results 121 to 130 of about 798,781 (261)

Modeling of fractional order DPG model insight global warming and pollution effect on desertification for control mechanism. [PDF]

Sci Rep
Farman M, Jamil K, Jamil S, Padder A, Ahmad H, Dehingia K, Bayram M.   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The private solution trap in collective action problems across 34 nations. [PDF]

Proc Natl Acad Sci U S A
Malthouse E, Pilgrim C, Sgroi D, Accerenzi M, Alfonso A, Ashraf RU, Baard M, Banerjee S, Belianin A, Bhattacharjee S, Bhattacharya M, Brañas-Garza P, Cárdenas JC, Carriquiry M, Choi S, Clochard GJ, Denzon EE, Dessoulavy-Sliwinski B, Dini G, Dong L, Ertl A, Exadaktylos F, Filiz-Ozbay E, Flecke SL, Galeotti F, Garcia-Muñoz T, Hanaki N, Hollard G, Horn D, Huang L, İriş D, Kiss HJ, Koch J, Kovářík J, Kwarteng OKB, Lange A, Leites M, Leung TH, Lim W, Morren M, Nockur L, Okyere CY, Oudah M, Ozkes AI, Page L, Park J, Pfattheicher S, Proestakis A, Ramos C, Ramos-Sosa M, Ashraf MS, Sanjaya MR, Schwaiger R, Sene O, Song F, Spycher S, Staněk R, Tanchingco N, Tavoni A, Te Velde V, Vázquez-De Francisco MJ, Visser M, Wang JT, Wang W, Weng WC, Werner K, Wijayanti A, Winkler R, Wooders J, Ying L, Zhen W, Hills T.   +71 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Making the Case for Dental Therapists in the United States. [PDF]

Ann Glob Health
Nguyen TM, Kuntzelman KA, Fleming E.
europepmc   +1 more source

Climatic changes: Global causes, global consequences, global solution

, 2013
Ključni uzrok klimatskih promena u savremenosti nalazi se u karakteristici kapitalizma koji počiva na ideji o maksimalizaciji profita. Dakle, radi se o sistemskoj karakteristici.Trka za zaradom bez obzira na posledice po prirodu, uspesi ubrzane industrijalizacije, nastojanje čoveka da ostvaruje sve nove i nove potrebe koje mu se rađaju (od upotrebe ...
Šuvaković, Uroš, Nadić, Darko P.
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Research on agricultural development issues based on comprehensive optimization strategy. [PDF]

Sci Rep
Dayou H, Jieyun LI, Ya W, Susu G, Xinran W, Xianchao W.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Existence of global weak solutions for a p-Laplacian inequality with strong dissipation in noncylindrical domains

Electronic Journal of Differential Equations, 2022
Jorge Ferreira, Erhan Piskin, Mohammad Shahrouzi, Sebastiao Cordeiro, Carlos Alberto Raposo   +4 more
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