Results 131 to 140 of about 947,098 (315)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The politics of land deals - a comparative analysis of global land policies on large-scale land acquisition

open access: yes, 2014
Due to current crises, large-scale land acquisition is becoming a topic of growing concern. Public data from the ‘Land Matrix Global Observatory’ project demonstrates that in low- and middle-income countries, since 2000, 1,419 large-scale land deals ...
Verhoog, S.M.   +1 more
core  

Blowup and existence of global solutions to nonlinear parabolic equations with degenerate diffusion

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we consider the degenerate parabolic equation $$ u_t-\hbox{div}(|\nabla u|^{p-2}\nabla u) =\lambda u^m+\mu|\nabla u|^q $$ on a smoothly bounded domain $\Omega\subseteq\mathbb{R}^N\; (N\geq2)$, with homogeneous Dirichlet boundary ...
Zhengce Zhang, Yan Li
doaj  

Towards the Prediction of Global Solution State Properties for Hydrogen Bonded, Self-Associating Amphiphiles. [PDF]

open access: yesChemistry, 2018
White LJ   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Nonexistence of positive global solutions to the differential equation $u''(t)-t^{-p-1} u^{p}=0$

open access: yesElectronic Journal of Differential Equations, 2016
A blow-up result for positive solutions to the differential equation $u''(t)-t^{-p-1} u^{p}=0$ is derived. Our result is different from the one obtained in the [1], and our conditions are less restrictive.
Ahmed Alsaedi, Bashir Ahmad
doaj  

Generalized result on the global existence of positive solutions for a parabolic reaction-diffusion model with an m × m diffusion matrix

open access: yesDemonstratio Mathematica
The aim of this work is to study the global existence in time of solutions for the tridiagonal system of reaction-diffusion by order mm. Our techniques of proof are based on compact semigroup methods and some L1{L}^{1}-estimates.
Barrouk Nabila, Abdelmalek Karima
doaj   +1 more source

Dynamics of Hepatitis B Virus Transmission with a Lévy Process and Vaccination Effects

open access: yesMathematics
This work proposes a novel stochastic model describing the propagation dynamics of the hepatitis B virus. The model takes into account numerous disease characteristics, and environmental disturbances were collected using Lévy jumps and the conventional ...
Sayed Murad Ali Shah   +3 more
doaj   +1 more source

The movement of multidrug-resistant tuberculosis across borders in East Africa needs a regional and global solution. [PDF]

open access: yesPLoS Med, 2015
Cain KP   +9 more
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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