Results 141 to 150 of about 947,098 (315)
Mechatronic Design of Low-Cost Control Systems for Rehabilitation and Assisting Devices
In this chapter, authors focus on mechatronic solutions for low-cost control devices for the homecare of elderly and people with reduced mobility, having the goal of assisting people in daily-life activities.
Ottaviano, E. +5 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Demographic Change and Policy Responses: Implications for the Global Economy [PDF]
The fertility declines associated with the final phase of the global demographic transition have led to slower population growth and accelerated ageing in developed countries and in several advanced developing countries. A global demographic and economic
Qun Shi, Rod Tyers
core
Nonexistence of positive global solutions to the differential equation $u''-t^{-p-1}u^p=0$
In this article we consider the ordinary differential equation $$ u'' -t^{-p-1} u^p =0. $$ We show the blow-up for solutions of this equation, under certain on the initial data.
Meng-Rong Li +3 more
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Global food crisis, this time : a dossier
“In this dossier, researchers from Focus on the Global South write about various aspects of the current crisis, its causes, and how it is impacting countries in Asia.
Bello, Walden +4 more
core
Critical exponent for a damped wave system with fractional integral
We shall present the critical exponent $$ F(p, q,\alpha):=\max\big\{\alpha+\frac{(\alpha+1)(p+1)}{pq-1}, \alpha+\frac{(\alpha+1)(q+1)}{pq-1}\big\}-\frac{1}{2} $$ for the Cauchy problem $$\displaylines{ u_{tt}-u_{xx}+u_t=J_{0|t}^{\alpha}(|v|^{p}),
Mijing Wu, Shengjia Li, Liqing Lu
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

