Results 141 to 150 of about 8,988,058 (267)
A parabolic-hyperbolic free boundary problem modeling tumor growth with drug application
Electronic Journal of Differential Equations, 2010 In this article, we study a free boundary problem modeling the growth of tumors with drug application. The model consists of two nonlinear second-order parabolic equations describing the diffusion of nutrient and drug concentration, and three ...
Ji-Hong Zhao
doaj
Global Public Health Data Innovation [PDF]
CDC\u2019s Global Public Health Data Innovation (GPHDI) aims to address key barriers to effective use of data in public health response. This three-year initiative is supported by investment from the 2021 U.S. American Rescue Plan Act.
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Pullback attractors for non-autonomous parabolic equations involving Grushin operators
Electronic Journal of Differential Equations, 2010 Using the asymptotic a priori estimate method, we prove the existence of pullback attractors for a non-autonomous semilinear degenerate parabolic equation involving the Grushin operator in a bounded domain.
Cung The Anh
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Division of Global Health Protection (DGHP) [PDF]
Protecting the health and safety of Americans and people around the world 24/7To ensure global health security, every country needs a robust public health system that can rapidly respond to emergencies.
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Dynamical behavior in a reaction-diffusion system with prey-taxis
Electronic Journal of Differential Equations, 2022 Yingwei Song, Tie Zhang, Jinpeng Li
doaj
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source