Results 131 to 140 of about 9,926,522 (389)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Impact of heterogeneity on the dynamics of an SEIR epidemic model
Mathematical Biosciences and Engineering, 2012 An SEIR epidemic model with an arbitrarily distributed exposed stage is revisited to study the impact of heterogeneity on the spread of infectious diseases.
Zhisheng Shuai, P. van den Driessche
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modelling the effect of immigration on drinking behaviour
Journal of Biological Dynamics, 2017 A drinking model with immigration is constructed. For the model with problem drinking immigration, the model admits only one problem drinking equilibrium.
Hong Xiang +2 more
doaj +1 more source
Analysis of a model for the effects of an external toxin on anaerobic digestion
Mathematical Biosciences and Engineering, 2012 Anaerobic digestion has been modeled as a two-stage process using coupled chemostat models with non-monotone growth functions, [9]. This study incorporates the effects of an external toxin.
Marion Weedermann
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Global Temporal and Geographic Stability of Brines on Present-day Mars
, 2020 V. F. Chevrier +3 more
openalex +1 more source
Global Stability of a Rational Difference Equation [PDF]
, 2010 Tang Guo-Mei, Lin-Xia Hu, Ma Gang
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source