Results 111 to 120 of about 3,005 (252)

Facets of the Tropical High-Cloud Feedback in a Global Storm-Resolving Model

Abstract Tropical high clouds are the cloud type that contributes most to the uncertainty in climate sensitivity, as their feedback on global warming remains poorly constrained. One reason for this is that global circulation models (GCMs) do not resolve the full spectrum of high clouds, ranging from thin cirrus to thick deep convective ...
Jakob Deutloff, Stefan Buehler, Julia Windmiller, Ann Kristin Naumann   +3 more
openaire   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Multiscale Interactions in the Life Cycle of a Tropical Cyclone Simulated in a Global Cloud-System-Resolving Model. Part I: Large-Scale and Storm-Scale Evolutions*

, 2010
The Nonhydrostatic Icosahedral Atmospheric Model (NICAM), a global cloud-system-resolving model, successfully simulated the life cycle of Tropical Storm Isobel that formed over the Timor Sea in the austral summer of 2006.
Hiroaki Miura, Tomoe Nasuno, Masaki Satoh, Yuqing Wang, Wataru Yanase, Hironori Fudeyasu   +5 more
core   +1 more source

Single‐Atom Pt Anchoring on Self‐Doped ZrO2@G‐C3N4 Nanostructure Enables Efficient Photocatalytic Seawater Hydrogen Evolution

Advanced Science, EarlyView.
Grain‐like Zr3+‐ZrO2 and Pt single atoms are integrated into an S‐scheme Zr3+‐ZrO2@g‐C3N4 heterostructure to enable efficient visible‐light‐driven seawater hydrogen production. The combined effect of Pt single‐atom sites and the S‐scheme charge‐transfer pathway accelerates carrier separation, preserves strong redox ability, and markedly enhances ...
Hezheng Sun, Yifan Guo, Xin Yu, Yajie Tian, Feng Gao, Bin Wang, Yanting Tang, Dani S. Assi, Vellaisamy A. L. Roy   +8 more
wiley   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Modelling of elevated mesoscale convective systems [PDF]

, 2012
Elevated convection occurs when convection originates from above the boundary layer. The interaction of an elevated storm with the stable layer beneath it often generates features such as waves and bores that maintain the convection.
White, Bethan Alice
core  

ICON Simulations Suggest Model-Dependent Cloud Feedbacks in Global Storm-Resolving Models

Abstract Climate feedbacks, key determinants of Earth’s temperature response to radiative forcing, remain uncertain, largely because of challenges in representing cloud and convective processes. Global storm-resolving models (GSRMs), which explicitly resolve deep convection, have recently emerged as a promising alternative to conventional ...
Alejandro Uribe, Malena Contizanetti, Frida A.-M Bender, Thorsten Mauritsen   +3 more
openaire   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Multiscale Interactions in the Life Cycle of a Tropical Cyclone Simulated in a Global Cloud-System-Resolving Model. Part II: System-Scale and Mesoscale Processes*

, 2010
The life cycle of Tropical Storm Isobel was simulated reasonably well in the Nonhydrostatic Icosahedral Atmospheric Model (NICAM), a global cloud-system-resolving model.
Hiroaki Miura, Tomoe Nasuno, Masaki Satoh, Yuqing Wang, Wataru Yanase, Hironori Fudeyasu   +5 more
core   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source