Results 131 to 140 of about 55,169 (227)

Convective transport of formaldehyde to the upper troposphere and lower stratosphere and associated scavenging in thunderstorms over the central United States during the 2012DC3 study [PDF]

, 2016
Apel, E, Barth, MC, Bela, M, Betten, D, Biggerstaff, MI, Blake, DR, Blake, N, Campos, T, Cantrell, C, Crawford, JH, Diskin, GS, Flocke, F, Fried, A, Froyd, K, Hills, A, Hornbrook, R, Li, Y, Luo, ZJ, Mikoviny, T, Olson, J, Peischl, J, Pickering, K, Pollack, I, Richter, D, Riemer, DD, Rutledge, S, Sachse, G, Schroeder, JR, Walega, J, Weibring, P, Weinheimer, A, Wisthaler, A, Woods, S   +32 more
core   +1 more source

Flexible 3D Multi‐Material Printing beyond Layer‐by‐Layer Constraints via Sequential Multi‐Printer Fabrication

Advanced Materials Technologies, EarlyView.
We developed a flexible multi‐material printing strategy that employs sequential printing with different printers. This combined use of printers expands the accessible material scope. Moreover, incorporating Xolography as a sequential step enables support‐free, contactless printing, thereby enhancing structural design flexibility beyond conventional ...
Kun Zhou, Cyrille Boyer
wiley   +1 more source

The Precipitation Response to Warming and CO2 Increase: A Comparison of a Global Storm Resolving Model and CMIP6 Models

Geophysical Research Letters
Global storm‐resolving models (GSRMs) that can explicitly resolve some of deep convection are now being integrated for climate timescales. GSRMs are able to simulate more realistic precipitation distributions relative to traditional Coupled Model ...
Ilai Guendelman, Timothy M. Merlis, Kai‐Yuan Cheng, Lucas M. Harris, Christopher S. Bretherton, Maximilien Bolot, Linjiong Zhou, Alex Kaltenbaugh, Spencer K. Clark, Stephan Fueglistaler   +9 more
doaj   +1 more source

On–Off Switchable Micromotors for Use in Steerable Microvehicles

Advanced Robotics Research, EarlyView.
Electrically controllable micromotors and microvehicles are developed by tuning the diffusion of the fuel. Self‐propelled micromotors using bubble propulsion show great promise for miniaturized devices with multiuse purposes such as cargo delivery and sensing. However, there is currently no method to electrically switch the micromotors on or off. Here,
Hugo Severinsson, Eswaran Murugasen, Jose G. Martinez, Edwin W. H. Jager   +3 more
wiley   +1 more source

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

Advanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee, Oliver James, Gaeun Jung, Doyun Lee, Yee‐Joon Kim   +4 more
wiley   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Contrasting Response of Mesoscale Convective Systems Occurrence Over Tropical Land and Ocean to Increased Sea Surface Temperature

Geophysical Research Letters
Mesoscale convective systems (MCSs) are pivotal in global energy/water cycles and typically produce extreme weather events. Despite their importance, our understanding of their future change remains limited, largely due to inadequate representation in ...
Wenhao Dong, Ming Zhao, Lucas Harris, Kai‐Yuan Cheng, Linjiong Zhou, V. Ramaswamy   +5 more
doaj   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Detecting changes in large-scale metrics of climate in short integrations of a global storm-resolving model of the atmosphere

Environmental Research: Climate
Recent advances have allowed for integration of global storm resolving models (GSRMs) to a timescale of several years. These short simulations are sufficient for studying aggregated statistics of short-timescale and small spatial-scale phenomena; however,
Ilai Guendelman, Timothy M Merlis, Kai-Yuan Cheng, Lucas M Harris, Christopher S Bretherton, Maximilien Bolot, Linjiong Zhou, Alex Kaltenbaugh, Spencer K Clark, Stephan Fueglistaler   +9 more
doaj   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source