Results 71 to 80 of about 1,755,386 (294)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
M3.5 ‐ Organic plant breeding in a systems‐based approach and integration of organic plant breeding in value chain partnerships [PDF]
, 2019 Developing organic breeding is a key challenge for the organic sector. It is necessary to better adapt varieties to the specific needs of the organic sector (disease resistance, taste, weed suppressing ability, etc).
Messmer, Monika M. +2 more
core
, 2008 The anisotropic XXZ spin-1/2 Heisenberg chain is studied using renormalization-group theory. The specific heats and nearest-neighbor spin-spin correlations are calculated thoughout the entire temperature and anisotropy ranges in both ferromagnetic and ...
A. Klümper +9 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Market-Driven Management and Global Supply Chain [PDF]
Globalization and over-supply have pushed companies to face new competitive challenges. In such a competitive space, a new approach in managing the supply chains and the consequent optimization of material flows and intangible assets plays a crucial role
Lorenzo Petretto, Monica Faraoni
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
ESTRATÉGIA DE INTERNACIONALIZAÇÃO ATRAVÉS DE UPGRADING FUNCIONAL
Contextus, 2012 This article analyzes the Brazilian companies’ participation in global value chains, focusing on a footwear company. Most companies of this sector concentrated their efforts through indirect exports, meaning a reactive strategy in the global chain.
Eduardo Smaniotto +2 more
doaj
Sustainable Business and Global Supply Chains in ASEAN: Escaping the Middle- Income Trap
American Journal of Business Science PhilosophyThis study explores the influence of sustainable business strategies and facilitative policy frameworks on ASEAN companies' upgrading and integration into global supply chains (GSCs).
Masatoshi Hara
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Multinational firms, global value chains and the organization of technology transfer [PDF]
This paper combines insights from different streams of literature to develop a more comprehensive framework for the analysis of technology transfer via value chain relationships. We integrate the existing literature in three ways.
Antonello Zanfei, Federica Saliola
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