Results 81 to 90 of about 472,314 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Existence of Mickey Mouse as The Walt Disney Company’s Mascot in the Global Value Chain Perspective

, 2019
Artikel ini berfokus pada eksistensi Mickey Mouse sebagai maskot Walt Disney Company berdasarkan perspektif global value chain. Sebagai mascot resmi, Mickey Mouse telah bertahan lama sejak tahun 1928 sampai saat ini, melalui karya yang telah dihasilkan ...
Syora Alya Eka Putri; Rombak Media
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Aerospace Industry: Current Status and Trends of the Global Value Chain [PDF]

The aerospace industry, characterized by its high value-added nature and strong ties to national governments, plays a crucial role in global value chains (GVCs).
Inter-American Development Bank
core   +1 more source

A Taxonomy for selecting global supply chain strategies. [PDF]

, 2006
This paper addresses the increasingly important question of supply chain design for global operations. With the rise of off-shore sourcing and the simultaneous need for improved responsiveness to customer demand, the choice of supply chain strategy is ...
Towill, Denis R., Christopher, Martin, Peck, Helen, Towill, Denis Royston   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Brazil, South Korea, and Global Value : A Tale of Two Countries

, 2020
O “ Brazil, South Korea, and Global Value : A Tale of Two Countries ” é um dos cinco short policy papers desenvolvidos para o projeto “Brazilian Global Value Chain Initiative – Understanding the South Korean Best Practices” (além do relatório principal ...
Canuto, Otaviano
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effects of the crisis on the automotive industry in developing countries : a global value chain perspective [PDF]

This paper applies global value chain analysis to study recent trends in the global automotive industry. The authors pay special attention to the effects of the recent economic crisis on the industry in developing countries. The principal finding is that
Sturgeon, Timothy J., Van Biesebroeck, Johannes   +1 more
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The Importance of the Fourth Industrial Revolution in Global Value Chains

, 2020
O “ The Importance of the Fourth Industrial Revolution in Global Value Chains ” é um dos cinco short policy papers desenvolvidos para o projeto “Brazilian Global Value Chain Initiative – Understanding the South Korean Best Practices” (além do relatório ...
Okuno, Marcelle Torres Alves
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