Results 81 to 90 of about 1,744,467 (339)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Pricing and distribution in global value chain regulation

open access: yesLeiden Journal of International Law
Global value chains (GVCs) function as a distributive arrangement at a global scale, generating and relocating wealth while often exacerbating inequalities across and within countries. The recent rise in GVC-related regulation must hence also be assessed
Klaas Hendrik Eller
doaj   +1 more source

Global Value Chain of Indonesian Pulp and Paper Industry

open access: yesJurnal Manajemen & Agribisnis, 2018
Global Value Chain (GVC) has been a global phenomenon since 1980s when export values no longer represented the actual benefit of a country’ economic measure.
Tauhid Ahmad   +3 more
doaj   +1 more source

WHY TRANSACTION COSTS IMPEDE SMALLHOLDER FARMERS’ PARTICIPATION INTO EXPORT ORGANIC MARKETS [PDF]

open access: yes, 2014
s There have been growing trends of exports from countries dominated by smallholder agriculture to many of developed world (Kledal and Kwai, 2010). This shows that smallholders’ farmers development perspectives have gained interests in global markets ...
Karantininis, Kostas   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The drivers of global value chain (GVC) participation in EU member states

open access: yesEconomic Research-Ekonomska Istraživanja, 2019
Integration within the EU single market increases the interconnection and interdependence of the EU economies.
Ines Kersan-Škabić
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Market-Driven Management and Global Supply Chain [PDF]

open access: yes
Globalization and over-supply have pushed companies to face new competitive challenges. In such a competitive space, a new approach in managing the supply chains and the consequent optimization of material flows and intangible assets plays a crucial role
Lorenzo Petretto, Monica Faraoni
core  

CO-OPERATING TO COMPETE IN HIGH VELOCITY GLOBAL MARKETS: THE STRATEGIC ROLE OF FLEXIBLE SUPPLY CHAIN ARCHITECTURES [PDF]

open access: yes
Continued value creation is paramount for the survival of firms competing in today's high velocity global business environment. This paper presents a conceptual framework for understanding how firms can create and capture value within a highly volatile ...
Gow, Hamish R.   +2 more
core   +4 more sources

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