Results 111 to 120 of about 5,140,187 (303)

Climate extremes in Europe at 1.5 and 2 degrees of global warming

open access: yesEnvironmental Research Letters, 2017
There is an international effort to attempt to limit global warming to 1.5 °C above pre-industrial levels, however, there is a lack of quantitative analysis on the benefits of holding global warming to such a level.
Andrew D King, David J Karoly
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Is the recently enhanced mesoscale convective systems in East Asia due to global warming or decadal variability?

open access: yesEnvironmental Research Letters
Since the beginning of 21st century, mesoscale convective systems (MCSs) precipitation in the Yangtze River Basin (YRB) has increased by approximately 25% per decade. Given the concurrent global warming, it is crucial to distinguish the relative roles of
Zhongxi Lin   +4 more
doaj   +1 more source

Global Warming – Our Greatest Challenge

open access: yesResearch and Review Journal of Nondestructive Testing
The current state of Earth’s climate is the result of a long-lasting, continuous development: it is a snapshot from a film of the Earth’s history that has lasted around 4.5 billion years and is still running. Climate fluctuations are documented by
Peter Lemke
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Global Warming: Solutions

open access: yes, 2008
This program looks at new solutions that change our energy sources away from fossil fuels. In ten years we an be free of our dependence on fossil fuels and at the same time reverse Global Warming. All of the solutions are dependant on the choices we make

core  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Degrees of change: Steps towards an Ontario global warming strategy

open access: yes, 1991
This report discusses: 1. A survey of the most promising policy measures and technologies to reduce carbon dioxide emissions; estimates of their potential to reduce provincial carbon emissions: and discussion of the primary market and institutional ...
Ontario Global Warming Coalition
core  

Oregon climate action roadmap to 2030, commission recommendations

open access: yes, 2023
This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 27-28).Mode of ...

core  

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