Results 101 to 110 of about 5,379,926 (308)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Climate extremes in Europe at 1.5 and 2 degrees of global warming
Environmental Research Letters, 2017 There is an international effort to attempt to limit global warming to 1.5 °C above pre-industrial levels, however, there is a lack of quantitative analysis on the benefits of holding global warming to such a level.
Andrew D King, David J Karoly
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Environmental Research LettersSince the beginning of 21st century, mesoscale convective systems (MCSs) precipitation in the Yangtze River Basin (YRB) has increased by approximately 25% per decade. Given the concurrent global warming, it is crucial to distinguish the relative roles of
Zhongxi Lin +4 more
doaj +1 more source
Global Warming – Our Greatest Challenge
Research and Review Journal of Nondestructive TestingThe current state of Earth’s climate is the result of a long-lasting, continuous development: it is a snapshot from a film of the Earth’s history that has lasted around 4.5 billion years and is still running. Climate fluctuations are documented by
Peter Lemke
doaj +1 more source
American evangelicals and global warming
, 2013 American evangelicals have long played a significant role in American culture and politics. Drawing from a nationally representative survey, this article describes American evangelicals’ global warming risk assessments and policy preferences and tests ...
Smith, N., Leiserowitz, A.
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Oregon Task Force on Global Warming: report to the Governor and Legislature
, 1990 pt 1. Possible impacts on Oregon from global warming -- pt. 2. State agency recommendations and proposed actionsThis archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program.
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Oregon Global Warming Commission roadmap to 2020: phase 1 summary report
, 2011 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Oct.
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