Results 91 to 100 of about 5,379,926 (308)

Scaled biotic disruption during early Eocene global warming events [PDF]

, 2012
Late Paleocene and early Eocene hyperthermals are transient warming events associated with massive perturbations of the global carbon cycle, and are considered partial analogues for current anthropogenic climate change.
Murphy, B.H., Edgar, K.M., Bown, P.R., P. R. Bown, Sluijs, A., B. H. Murphy, Pälike, H., Zachos, J. C., Bolton, Clara, Edgar, K. M.; id_orcid, Bolton, C.T., Paelike, H., Edgar, Kirsty M., Gibbs, S.J., Gibbs, Samantha J., Pälike, Heiko, Murphy, B. H., C. T. Bolton, A. Sluijs, H. Pälike, K. M. Edgar, J. C. Zachos, Zachos, J.C., S. J. Gibbs, Edgar, K. M., Marine Palynology, Marine palynology and palaeoceanography, Bown, P. R., Bown, Paul R., Murphy, Brandon H., Sluijs, Appy, Bolton, C. T., Gibbs, S. J., Zachos, James C., Research Programme in Earth Sciences Utrecht (DES / IVAU)   +34 more
core   +2 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Global warming and water sustainability

E3S Web of Conferences, 2014
Water is a primary element in the human diet and a necessary resource for the agriculture. In addition, industrial practices need a growing amount of water.
Cassardo Claudio
doaj   +1 more source

Mitigation versus compensation in global warming policy [PDF]

Policy discussions on global warming are focused on mitigation and adaptation. Here the role of ex post compensation as a substitute for ex ante mitigation is considered.
Ross McKitrick
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Reduced spread of simulated global warming patterns among CMIP6 models with elevated level of warming

Environmental Research Letters
Uneven economic impacts of climate change have been largely caused by differentiated warming rates across different geographical regions, affecting the lives of the majority of world’s population. Historical and future warming rates are commonly obtained
Yilin Meng, Yan Yu, Ji Nie
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Q&A: Global warming: No easy answers

California Agriculture, 2000
California Agriculture - All ...
F Rowland
doaj  

Asymmetric Response to Global Warming

Journal of Education, Health and Sport
The study aims to develop critical thinking in the context of global warming, analyze existing approaches to solving this problem, and propose alternative methods of combating climate change. Materials and methods: Scientific literature was analyzed,
Anatoliy Zhukov, Walery Zukow
doaj   +1 more source