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Global Warming – Our Greatest Challenge

open access: yesResearch and Review Journal of Nondestructive Testing
The current state of Earth’s climate is the result of a long-lasting, continuous development: it is a snapshot from a film of the Earth’s history that has lasted around 4.5 billion years and is still running. Climate fluctuations are documented by
Peter Lemke
doaj   +1 more source

GLOBAL WARMING BETWEEN SCIENCE AND POLITICS

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2015
During the last three decades, the scientific theory of global warming has become a political ideology. Significant political components are found both in the premises and (especially) in the consequences.
Eugen Străuțiu
doaj   +1 more source

Economic vitality in a transition to sustainability [PDF]

open access: yes
The good news is that many of the solutions to this extraordinary problem are within reach. Many of the solutions to global warming are not only feasible, they are economically and socially beneficial. While some claim that addressing global warming will
Goodwin, Neva
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Global Warming Has Accelerated Significantly

open access: yesGeophysical Research Letters
Recent record‐hot years have caused discussion over whether global warming has accelerated. Previous analysis found acceleration (i.e., increase in warming rate) has not yet reached a 95% confidence level, given natural temperature variability. We remove
G. Foster, S. Rahmstorf
doaj   +1 more source

Climate extremes in Europe at 1.5 and 2 degrees of global warming

open access: yesEnvironmental Research Letters, 2017
There is an international effort to attempt to limit global warming to 1.5 °C above pre-industrial levels, however, there is a lack of quantitative analysis on the benefits of holding global warming to such a level.
Andrew D King, David J Karoly
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Global Warming and Agriculture: Impact Estimates by Country [PDF]

open access: yes
How will global warming affect developing countries, which rely heavily on agriculture as a source of economic growth? William Cline asserts that developing countries have more at risk than industrial countries as global warming worsens.
William R. Cline
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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