Results 31 to 40 of about 5,379,926 (308)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Environmental Research: ClimateThere is growing concern about heat waves caused by climate change. In Japan, the population is rapidly aging, and protecting older people from heatstroke is attracting public attention.
Keita Honjo +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Journal of Hydrology: Regional StudiesStudy region: Four small reservoirs in northwestern Iran varying in size and shape—Taham, Kinevars, Boeen, and Chargar—serve as major drinking and irrigation water sources for semi-arid Zanjan Province.
Z. Masoumi, Mohammad J. Tourian
doaj +1 more source
Global Warming Reshapes European Pyroregions
Earth's Future, 2023 Wildland fire is expected to increase in response to global warming, yet little is known about future changes to fire regimes in Europe. Here, we developed a pyrogeography based on statistical fire models to better understand how global warming reshapes ...
Luiz Felipe Galizia +5 more
doaj +1 more source
Global Warming, Global Warming Pause and the Role of CO2 [PDF]
Proceedings of Accretion Processes in Cosmic Sources — PoS(APCS2016), 2018 We discuss several aspects of the phenomenon called Global Warming and refrain from any con- clusions. We leave the reader to draw his conclusions about the series of observations presented here. The phenomenon called Global Warming or in the new name Climate Change, refers to the be- havior of the ’Temperature of the Earth’ as a function of time. The
openaire +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Global (post) media warming [PDF]
Kaiak, 2018 The "environmental violence", under the aspect of global warming, seems now the first violence to be faced, alongside those of wars. It has crossed with the progressive erosion of the symbolic orders established in the twentieth century. The intersection
Vincenzo Cuomo
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Discover Public HealthBackground Noise pollution is regarded the third most hazardous form of pollution, following air and water pollution. Nightclubs are significant sources of elevated noise levels that pose health risks to employees, patrons, and nearby residents.
Mohamed Mustapha Abu +3 more
doaj +1 more source