Results 41 to 50 of about 5,140,187 (303)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Assessing the impact of climate and population changes on heatstroke incidence in Saitama City, Japan

open access: yesEnvironmental Research: Climate
There is growing concern about heat waves caused by climate change. In Japan, the population is rapidly aging, and protecting older people from heatstroke is attracting public attention.
Keita Honjo   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Absolute validation of SWOT measurements over small reservoirs using legacy photogrammetric DEMs: A case study in Zanjan Province, Iran

open access: yesJournal of Hydrology: Regional Studies
Study region: Four small reservoirs in northwestern Iran varying in size and shape—Taham, Kinevars, Boeen, and Chargar—serve as major drinking and irrigation water sources for semi-arid Zanjan Province.
Z. Masoumi, Mohammad J. Tourian
doaj   +1 more source

Future water storage changes over the Mediterranean, Middle East, and North Africa in response to global warming and stratospheric aerosol intervention [PDF]

open access: yesEarth System Dynamics
Water storage plays a profound role in the lives of people across the Middle East and North Africa (MENA) as it is the most water-stressed region worldwide.
A. Rezaei   +4 more
doaj   +1 more source

Global Warming Reshapes European Pyroregions

open access: yesEarth's Future, 2023
Wildland fire is expected to increase in response to global warming, yet little is known about future changes to fire regimes in Europe. Here, we developed a pyrogeography based on statistical fire models to better understand how global warming reshapes ...
Luiz Felipe Galizia   +5 more
doaj   +1 more source

Global Warming, Global Warming Pause and the Role of CO2 [PDF]

open access: yesProceedings of Accretion Processes in Cosmic Sources — PoS(APCS2016), 2018
We discuss several aspects of the phenomenon called Global Warming and refrain from any con- clusions. We leave the reader to draw his conclusions about the series of observations presented here. The phenomenon called Global Warming or in the new name Climate Change, refers to the be- havior of the ’Temperature of the Earth’ as a function of time. The
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Global (post) media warming [PDF]

open access: yesKaiak, 2018
The "environmental violence", under the aspect of global warming, seems now the first violence to be faced, alongside those of wars. It has crossed with the progressive erosion of the symbolic orders established in the twentieth century. The intersection
Vincenzo Cuomo
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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