Results 51 to 60 of about 5,379,926 (308)

Tropical atmospheric circulation changes under global warming [PDF]

, 2013
This PhD thesis consists of three scientific articles. In the first one the tropical sea level pressure (SLP) response under global warming is investigated in a multi-model ensemble (MMEns) of climate models from the 3rd phase of the Coupled Model ...
Bayr, Tobias
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Global warming is global energy storage

, 2008
The global air temperature increase is an inadequate measure of global warming, which rather should be considered in terms of energy. The ongoing global warming means that heat has been accumulating since 1880, in air, ground, and water.
Gervet, Bruno, Nordell, Bo
core   +1 more source

Arctic dimension of global warming

Лëд и снег, 2015
A brief assessment of the global warming in the Arctic climate system with the emphasis on sea ice is presented. The Arctic region is coupled to the global climate system by the atmosphere and ocean circulation that providesa major contribution to the ...
G. V. Alekseev
doaj   +1 more source

Present global warming: a justifiable and stable metric for evaluating short-lived climate pollutants

Environmental Research Letters, 2022
The impacts of short-lived climate pollutants (SLCPs) such as methane are typically described using metrics that compare their climate impacts to carbon dioxide’s climate impact.
Andrew E Pomerantz, Robert L Kleinberg
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Urban sprawl, global warming, and the empire of capital

, 2009
This far-reaching and penetrating study sheds new light on the role of the United States in global warming. Shortly after the Second World War, urban development in the United States became an important spur for the global economy, creating demand for ...
Gonzalez, George A
core   +3 more sources

Impacts of 1.5°C Global Warming on Natural and Human Systems [PDF]

, 2018
An IPCC Special Report on the impacts of global warming of 1.5°C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to the threat of climate change, sustainable development,
Rogelj, Joeri, Singh, Chandni, Mahowald, Natalie, Alexander, Lisa V., Hoegh-Guldberg, O., Gattuso, Jean Pierre, Okem, Andrew, Hayes, Katie, Petzold, Jan, Paz, Shlomit, Millar, Richard, Vautard, Robert, Wartenburger, Richard, Scheuffele, Hanna, Liverman, Diana, Jacob, D., Wehner, Michael, Payne, A., Zhang, Xuebin, Engelbrecht, F., Mehrotra, S., Bolaños, Tania Guillén, Tebboth, Mark, Diedhiou, A., Berry, Peter, Sylla, Mouhamadou B., Ebi, K., Achlatis, Michelle, Schleussner, Carl-Friedrich, Kanninen, Markku, Ley, Debora, Mitchell, Dann, Tschakert, Petra, Seneviratne, S. I., Cheung, William, Brown, S., Hasegawa, Tomoko, Hijioka, Y., Whyte, Felicia, Fischer, Hubertus, Hanasaki, Naota, Ellis, Neville, Notz, Dirk, Halim, Sharina Abdul, Scott, Daniel, Allen, Myles, Weyer, Nora M., Warren, R., Brilli, Lorenzo, Jung, Thomas, Jones, Chris, Zhou, G., Evans, Jason, Bindi, M., Craig, Marlies, Krinner, Gerhard, Boyer, Christopher, Greve, Peter, Slade, Raphael, Camilloni, I., Djalante, R., Lenton, Tim, Yohe, Gary, Stephenson, Tannecia, Mix, Alan C., Fuss, Sabine, Thomas, A., Fraedrich, Klaus, Buckeridge, Marcos, Oppenheimer, Michael, Séférian, Roland, Byers, Edward, Preuschmann, Swantje, Lawrence, David, Guiot, J., Hirsch, Annette, Zougmoré, Robert B., Petersen, Juliane, Stephenson, Kimberly, Meissner, Katrin J., Nurse, Leonard, Sillmann, Jana, Ganase, Anjani, Mintenbeck, Katja, McInnes, Kathleen, Olsson, Lennart, Rahman, Mohammad Feisal   +86 more
core  

Effects of Fuel Consumption of Commercial Turbofans on Global Warming

, 2009
Global Conference on Global Warming -- JUL 06-10, 2008 -- Istanbul, TURKEYWOS ...
Karakoç, Tahir Hikmet, Turan, Önder, Karakoç, T. Hikmet, Onder Turan, T. Hikmet Karakoc   +4 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source