Results 131 to 140 of about 7,739 (261)

Enterohemorrhagic Escherichia coli colonization of human colonic epithelium in vitro and ex vivo [PDF]

, 2015
Enterohemorrhagic E. coli (EHEC) are important foodborne pathogens causing gastroenteritis and more severe complications such as hemorrhagic colitis and hemolytic uremic syndrome.
B. A. McCormick, Richard Tighe, Stephanie Schüller, Steven B. Lewis, Vivienne Cook   +4 more
core   +1 more source

Cytokines Expression from Altered Anterior and Lateral Ventral Nuclei of the Murine Thalamus and Motor Deficits Following Sublethal Administration of Shiga Toxin 2 from Enterohemorrhagic <i>Escherichia coli</i> Involve the Induction of the Globotriaosylceramide Receptor

, 2022
David Arenas-Mosquera, Alípio Pinto, Natacha Cerny, Clara Berdasco, Adriana Cangelosi, Patricia Geoghegan, Emilio L. Malchiodi, Mauricio C. De Marzi, Jorge Goldstein   +8 more
openalex   +1 more source

Clinical relevance of globotriaosylceramide accumulation in Fabry disease and the effect of agalsidase beta in affected tissues.

Molecular Genetics and Metabolism, 2022
C. Tøndel, B. Thurberg, P. DasMahapatra, Nicole Lyn, M. Maski, Julie L. Batista, Kelly George, Hiren K. Patel, A. Hariri   +8 more
semanticscholar   +1 more source

Distributions of Globotriaosylceramide Isoforms, and Globotriaosylsphingosine and Its Analogues in an α-Galactosidase A Knockout Mouse, a Model of Fabry Disease

PLoS ONE, 2015
Fabry disease is caused by deficient activity of α-galactosidase A (GLA) and characterized by systemic accumulation of glycosphingolipids, substrates of the enzyme.
H. Sueoka, Mikio Aoki, T. Tsukimura, T. Togawa, H. Sakuraba   +4 more
semanticscholar   +1 more source

Enterohemorrhagic Escherichia coli with particular attention to the German outbreak strain O104:H4 [PDF]

, 2012
This review deals with the epidemiology and ecology of enterohemorrhagic Escherichia coli (EHEC), a subset of the verocytotoxigenic Escherichia coli (VTEC), and subsequently discusses its public health concern.
De Reu, K, De Zutter, Lieven, Joris, Adelheid, Vanrompay, Daisy, Verstraete, K   +4 more
core   +1 more source

Activator protein for the degradation of globotriaosylceramide by human alpha-galactosidase.

Journal of Biological Chemistry, 1983
An activator protein which stimulates the degradation of globotriaosylceramide by human hepatic alpha-galactosidase (alpha-D-galactoside galactohydrolase, EC 3.2.1.22) was isolated from human liver and purified some 1300-fold. The purified activator was heat stable up to 95 degrees C, its molecular weight was estimated at 20,000 by gel filtration ...
S, Gärtner, E, Conzelmann, K, Sandhoff
openaire   +2 more sources

PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]

, 2010
Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy, Gummuluru, Suryaram, Hanley, Timothy M., Viglianti, Gregory A.   +3 more
core   +5 more sources

A Case of a 50-Year-Old Woman with Typical Fabry Disease Who Showed Serial Electrocardiographic and Echocardiographic Changes over a 17-Year Period

Case Reports in Cardiology, 2019
Fabry disease (FD) is a progressive, X-linked lysosomal storage disorder caused by a deficiency of α-galactosidase A activity. Affected individuals accumulate globotriaosylceramide and glycosphingolipids in the lysosomes and cytoplasm of cells throughout
Su Nam Lee, Gee-Hee Kim, Ki-Dong Yoo
doaj   +1 more source

Clinical and Pathological Findings in Women with Fabry Disease [PDF]

, 2009
Introduction. Fabry disease is a rare metabolic disorder caused by the genetic deficiency of the lysosomal hydrolase alpha-galactosidase A, located on chromosome X.
Chan, KH, Chu, ACY, Ho, JWM, Ho, PWL, Ho, SL, Kung, MHW, Kwok, KHH, Liu, HF, Ramsden, David   +8 more
core   +1 more source

Caveolin-associated Accumulation of Globotriaosylceramide in the Vascular Endothelium of α-Galactosidase A Null Mice [PDF]

, 2007
Liming Shu, James A. Shayman
openalex   +1 more source