Trihexosylceramides - Open Access .click

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Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles in infancy: a population-based cohort study [PDF]

eLife, 2022
Background: The risk of adult onset cardiovascular and metabolic (cardiometabolic) disease accrues from early life. Infection is ubiquitous in infancy and induces inflammation, a key cardiometabolic risk factor, but the relationship between infection ...
Toby Mansell +15 more
doaj +6 more sources

Global Lipidome Profiling Revealed Multifaceted Role of Lipid Species in Hepatitis C Virus Replication, Assembly, and Host Antiviral Response [PDF]

Viruses, 2023
Hepatitis C virus (HCV) is a major human pathogen that requires a better understanding of its interaction with host cells. There is a close association of HCV life cycle with host lipid metabolism.
Khursheed Ul Islam +8 more
doaj +2 more sources

Structure of Trihexosylceramide Biosynthesized in Vitro

Journal of Biological Chemistry, 1973
Abstract Trihexosylceramide biosynthesized in vitro from lactosylceramide and UDP-galactose in the presence of a galactosyltransferase from rat spleen microsomes or bone marrow was shown by methylation to have the structure galactopyranosyl-α-(1 → 3)-galactopyranosyl-β-(1 → 4)-glucopyranosyl-β-(1 → 1)-ceramide.
P, Stoffyn, A, Stoffyn, G, Hauser
openaire +4 more sources

Sulfated Trihexosylceramide from Gastric Mucosa Containing N-Acetylglucosamine [PDF]

European Journal of Biochemistry, 1980
A new sulfated glycosphingolipid containing N-acetylglucosamine has been isolated from hog gastric mucosa by extraction with sodium acetate. Based on the results of partial acid hydrolysis, sequential degradation with specific glycosidases, and methylation analysis of the native and desulfated compound, the structure of this glycolipid is proposed to ...
A, Slomiany, B L, Slomiany, C, Annese
openaire +2 more sources

Mechanism for the biosynthesis of Forssman glycolipid from trihexosylceramide.

Journal of Biological Chemistry, 1980
The mechanism for the synthesis of Forssman glycolipid (GalNAc-alpha-GalNAc-beta-Gal-Gal-Glc-Cer) from trihexosylceramide (Gal-Gal-Glc-Cer, Hex3Cer) and radioactively labeled UDP-N-acetylgalactosamine catalyzed by particulate beta- and alpha-N-acetylgalactosaminyl-transferase of hamster NIL-2K cells was studied.
S, Kijimoto-Ochiai, N, Yokosawa, A, Makita +2 more
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Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan. [PDF]