Results 11 to 20 of about 382 (79)

Novel Relationship Between Plasmalogen Lipid Signatures and Carnosine in Humans [PDF]

open access: yesMolecular Nutrition &Food Research, Volume 65, Issue 20, October 2021., 2021
Carnosine has shown to improve glucose metabolism and cardiovascular risk. This study explores the relationship with the plasma lipidome by profiling >450 lipid species. Muscle carnosine and serum carnosinase‐1 activity (CN1) were negatively associated with 2‐h glucose and insulin sensitivity, respectively. This study identifies a strong association of
Jordi Mayneris‐Perxachs   +5 more
wiley   +4 more sources

Elevated lipid class concentrations in females with anorexia nervosa before and after intensive weight restoration treatment—A lipidomics study

open access: yesInternational Journal of Eating Disorders, Volume 56, Issue 12, Page 2260-2272, December 2023., 2023
Abstract Objective To study the plasma lipidome of patients with anorexia nervosa (AN) before and after weight restoration treatment and report associations with AN subtypes and oral contraceptive pill (OCP) usage. Methods Quantitative shotgun lipidomics analysis was used to study plasma lipids of 50 female patients with AN before and after weight ...
Alia Arif Hussain   +7 more
wiley   +1 more source

Discovery of lipid profiles in plasma‐derived extracellular vesicles as biomarkers for breast cancer diagnosis

open access: yesCancer Science, Volume 114, Issue 10, Page 4020-4031, October 2023., 2023
This study investigated the use of lipid profiles in plasma‐derived extracellular vesicles as non‐invasive biomarkers for diagnosing, staging, and subtyping breast cancer. Lipid profiling effectively discriminated breast cancer progression and subtypes, suggesting its potential as a promising approach to breast cancer management.
Lin Liu   +10 more
wiley   +1 more source

Glycosphingolipids in human parasites

open access: yesFEBS Open Bio, Volume 13, Issue 9, Page 1625-1635, September 2023., 2023
The parasites that infect humans and animals include protozoans and helminths (worms). Their secretions and cellular membranes contain complex glycomolecules including glycoproteins and glycolipids. A class of glycolipids shared between humans and parasites are the glycosphingolipids (GSLs) containing a lipid (ceramide) linked to a glycan ...
Richard D. Cummings
wiley   +1 more source

APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies

open access: yesAlzheimer's &Dementia, Volume 18, Issue 11, Page 2151-2166, November 2022., 2022
Abstract Introduction The apolipoprotein E (APOE) genotype is the strongest genetic risk factor for late‐onset Alzheimer's disease. However, its effect on lipid metabolic pathways, and their mediating effect on disease risk, is poorly understood. Methods We performed lipidomic analysis on three independent cohorts (the Australian Imaging, Biomarkers ...
Tingting Wang   +34 more
wiley   +1 more source

Correlation between metabolomic profile constituents and feline pancreatic lipase immunoreactivity

open access: yesJournal of Veterinary Internal Medicine, Volume 36, Issue 2, Page 473-481, March 2022., 2022
Abstract Background Feline pancreatic lipase immunoreactivity (fPLI) is commonly used to diagnose pancreatitis in cats (FP). Untargeted metabolomics has been extensively applied in human and veterinary medicine, but no metabolomic studies regarding FP have been conducted.
Magdalena Maria Krasztel   +5 more
wiley   +1 more source

Metabolite Characteristics in Tongue Coating from Damp Phlegm Pattern in Patients with Gastric Precancerous Lesion

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Objective. In this study, we analyzed the metabolite profile of the tongue coating of patients having gastric precancerous lesion (GPL) with damp phlegm pattern and proposed a mechanism of pathological transition. Methods. The changes in tongue‐coating metabolites in patients with GPL damp phlegm pattern were analyzed using GC‐TOF‐MS and UHPLC‐QE‐MS ...
Yifeng Xu   +7 more
wiley   +1 more source

Change of isoforms' spectra of α-l-fucosidase from human skin fibroblasts in intracellular storage of nonhydrolyzable substances [PDF]

open access: yes, 1995
The effect of exogenous and endogenous products storage in lysosomes on the activity and multiple forms of α-l-fucosidase from human skin fibroblasts was investigated.
Artykova, Gulbahar   +3 more
core   +1 more source

Role of Sphingolipids in the Pathobiology of Lung Inflammation

open access: yesMediators of Inflammation, Volume 2015, Issue 1, 2015., 2015
Sphingolipid bioactivities in the respiratory airways and the roles of the proteins that handle them have been extensively investigated. Gas or inhaled particles or microorganisms come into contact with mucus components, epithelial cells, blood barrier, and immune surveillance within the airways.
Riccardo Ghidoni   +3 more
wiley   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao   +12 more
wiley   +1 more source

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