Results 1 to 10 of about 14,058 (187)

Lipidomics of Glycosphingolipids [PDF]

Metabolites, 2012
Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base.
Hany Farwanah, Thomas Kolter
doaj   +4 more sources

Glycosphingolipids in human parasites

FEBS Open Bio, 2023
Glycosphingolipids (GSLs) are comprised of glycans (oligosaccharides) linked to a lipid containing a sphingosine moiety. They are major membrane components in cells of most animals, and importantly, they also occur in parasitic protozoans and worms that ...
Richard D. Cummings
doaj   +3 more sources

Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson’s disease [PDF]

Journal of Lipid Research
Alterations in sphingolipid metabolism have been implicated in the pathogenesis of Parkinson's disease (PD), yet findings regarding peripheral sphingolipid changes remain inconsistent.
Yu-Fong Peng, Szu-Ju Chen, Jeng-Lin Li, Chin-Hsien Lin, Ching-Hua Kuo   +4 more
doaj   +2 more sources

Aeromonas salmonicida binds α2-6 linked sialic acid, which is absent among the glycosphingolipid repertoires from skin, gill, stomach, pyloric caecum, and intestine

Virulence, 2022
Carbohydrates can both protect against infection and act as targets promoting infection. Mucins are major components of the slimy mucus layer covering the fish epithelia.
John Benktander, Henrik Sundh, Sinan Sharba, Susann Teneberg, Sara K. Lindén   +4 more
doaj   +1 more source

The repertoire of glycosphingolipids recognized by Vibrio cholerae. [PDF]

PLoS ONE, 2013
The binding of cholera toxin to the ganglioside GM1 as the initial step in the process leading to diarrhea is nowadays textbook knowledge. In contrast, the knowledge about the mechanisms for attachment of Vibrio cholerae bacterial cells to the intestinal
John Benktander, Jonas Ångström, Hasse Karlsson, Omid Teymournejad, Sara Lindén, Michael Lebens, Susann Teneberg   +6 more
doaj   +1 more source

Glycosphingolipids Recognized by Acinetobacter baumannii

Microorganisms, 2020
Acinetobacter baumannii is an opportunistic bacterial pathogen associated with hospital-acquired infections, including pneumonia, meningitis, bacteremia, urinary tract infection, and wound infections.
Miralda Madar Johansson, Mehjar Azzouz, Beatrice Häggendal, Karin Säljö, Henri Malmi, Anton Zavialov, Susann Teneberg   +6 more
doaj   +1 more source

Glycosphingolipids and neuroinflammation in Parkinson’s disease

Molecular Neurodegeneration, 2020
Parkinson's disease is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons of the nigrostriatal pathway and the formation of neuronal inclusions known as Lewy bodies.
Karim Belarbi, Elodie Cuvelier, Marie-Amandine Bonte, Mazarine Desplanque, Bernard Gressier, David Devos, Marie-Christine Chartier-Harlin   +6 more
doaj   +1 more source

Characterization of glycosphingolipids by direct inlet chemical ionization mass spectrometry

Journal of Lipid Research, 1980
Permethylated derivatives of cerebrosides and ceramide di-, tri-, tetra-, and penta-hexosides were analyzed by the direct inlet ammonia chemical ionization (CI) mass spectrometry. In the CI mass spectra, the fragment ions produced by the loss of methanol
T Ariga, T Murata, M Oshima, M Maezawa, T Miyatake   +4 more
doaj   +1 more source

Micellar properties of glycosphingolipids in aqueous media.

Journal of Lipid Research, 1984
The aggregation properties of neutral glycosphingolipids and gangliosides were investigated by ultracentrifugal sedimentation and gel permeation chromatography. Initially, glycosphingolipids in buffer formed high molecular aggregates.
B Ulrich-Bott, H Wiegandt
doaj   +1 more source

Glycosphingolipid Functions [PDF]

Cold Spring Harbor Perspectives in Biology, 2011
The combination of carbohydrate and lipid generates unusual molecules in which the two distinctive halves of the glycoconjugate influence the function of each other. Membrane glycolipids can act as primary receptors for carbohydrate binding proteins to mediate transmembrane signaling despite restriction to the outer bilayer leaflet.
openaire   +3 more sources