Results 41 to 50 of about 18,580 (229)
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Profiling of Glycosphingolipids with SCDase Digestion and HPLC-FLD-MS [PDF]
, 2021 Lipid components of cells and tissues feature a large diversity of structures that present a challenging problem for molecular analysis. Glycolipids from mammalian cells contain glycosphingolipids (GSLs) as their major glycolipid component, and these ...
Radhika, Chakraberty +2 more
core +2 more sources
Glycosphingolipids and drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006 Drug resistance, an all too frequent characteristic of cancer, represents a serious barrier to successful treatment. Although many resistance mechanisms have been described, those that involve membrane-resident proteins belonging to the ABC (ATP binding cassette) transporter superfamily are of particular interest.
Gouaze-Andersson, Valerie +1 more
openaire +2 more sources
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
New Results On Glycosphingolipids
, 1992 The occurrence of glycoconjugates (glycosphingolipids, glycoproteins, and glycosyl phosphates) as integral constituents of membranes and cell walls has recently stimulated great research activities.
Escher, B, Schmidt, RR
core +1 more source
Porcine intestinal glycosphingolipids recognized by Brachyspira hyodysenteriae
, 2023 Swine dysentery caused by Brachyspira hyodysenteriae is a disease present worldwide with an important economic impact on the farming business, resulting in an increased use of antibiotics.
Zalem, Dani, +3 more
core +1 more source
Apprehending ganglioside diversity: a comprehensive methodological approach[S]
Journal of Lipid Research, 2015 Gangliosides (GGs) make a wide family of glycosphingolipids ubiquitously expressed in mammalian tissues and particularly abundant in the brain and nervous system.
ElodieA.Y. Masson +5 more
doaj +1 more source
Journal of Lipid Research, 2010 Fast migrating cerebrosides (FMC) are derivatives of galactosylceramide (GalCer). The structures of the most hydrophobic FMC-5, FMC-6, and FMC-7 were determined by electrospray ionization linear ion-trap mass spectrometry (MS) and nuclear magnetic ...
Maria Podbielska +6 more
doaj +1 more source
T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease
Advanced Science, EarlyView.This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li +11 more
wiley +1 more source
Porcine intestinal glycosphingolipids recognized by F6-fimbriated enterotoxigenic Escherichia coli [PDF]
, 2014 One important virulence factor of enterotoxigenic Escherichia coli is their ability to adhere via fimbrial adhesins to specific receptors located on the intestinal mucosa. Here, the potential glycosphingolipid receptors of enterotoxigenic F6-fimbriated E.
Cox, Eric +4 more
core +1 more source